108279-65-8

Basic information

• Product Name: 6-chloro-4-methoxypyridine-2(1H)-one
• CAS NO: 108279-65-8
• Molecular Weight: 159.572
• Mol File: 108279-65-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-4-methoxypyridine-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-4-methoxypyridine-2(1H)-one(108279-65-8)
• EPA Substance Registry System: 6-chloro-4-methoxypyridine-2(1H)-one(108279-65-8)

Safety Data

• Hazardous Substances Data: 108279-65-8(Hazardous Substances Data)

Usage

Chemical class

Heterocyclic compound

Pyridine ring

Contains a chlorine atom at the 6th position and a methoxy group at the 4th position

Functional group

Ketone group at the 2nd position of the pyridine ring

Applications

Potential use in pharmaceutical and agrochemical industries as a building block for the synthesis of biologically active compounds

Value

Valuable intermediate for the development of novel drug molecules and crop protection agents

Upstream product

• 16063-69-7 2,4,6-trichloropyridine 
• 2587-00-0 2,6-dichloropyridine N-oxide 
• 2402-78-0 2,6-dichloropyridine 
• 108279-89-6 2-chloro-4,6-dimethoxypyridine 

Relevant articles and documents

Novel Annelation Method to Pyridine and Isoquinoline by Photochemical Means

Intramolecular photoaddition reactions of 2-(ω-alkenyl)isoquinolin-1(2H)-ones and 1-(ω-alkenyl)pyridin-2(1H)-ones were examined, and the regioselectivity and dependence of these reactions on the length of methylene chain in the alkenyl group were clarified.By utilizing these reactions, a synthetic route to indolizine and quinolizine derivates was elaborated.By an extension of this approach to the intermolecular reaction, 6-methoxy-3-methyl-1,2-dihydrocyclobutapyridin-4(3H)-one was synthesized from 4,6-dimethoxy-1-methylpyridin-2(1H)-one.Keywords-2+2 photocycloaddition; intramolecular photoaddition; photocycloreversion; annelation; indolizine; quinolizine; cyclobutapyridine; 4,6-dimethoxypyridin-2(1H)-one; 1-(ω-alkenyl)pyridin-2(1H)-one; 2-(ω-alkenyl)isoquinolin-1(2H)-one