108281-78-3 Usage
General Description
6-Bromo-3-methyl-1,2,4-triazolo[4,3-a]-pyridine is a chemical compound with the molecular formula C6H5BrN4. It is a heterocyclic compound containing a triazole ring and a pyridine ring, with a bromine atom attached to the triazole ring and a methyl group attached to the pyridine ring. 6-Bromo-3-methyl-1,2,4-triazolo[4,3-a]-pyridine is used in the synthesis of pharmaceuticals and agrochemicals, and it has also been studied for its potential biological activities, including its antimicrobial and anti-inflammatory properties. Its chemical structure and properties make it a valuable building block for the development of new molecules with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 108281-78-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,2,8 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 108281-78:
(8*1)+(7*0)+(6*8)+(5*2)+(4*8)+(3*1)+(2*7)+(1*8)=123
123 % 10 = 3
So 108281-78-3 is a valid CAS Registry Number.
108281-78-3Relevant articles and documents
Triazole compounds and preparation method and application thereof
-
Paragraph 0100-0105, (2019/10/05)
The invention provides triazole compounds and a preparation method and application thereof. The provided triazole compounds or pharmaceutically acceptable salts thereof have the structure shown as a formula (I), wherein R1, R2 and R3 are respectively and independently selected from -SO2R4, -SO2R5, COR6, H, and halogen; R4, R5 and R6 are respectively and independently selected from an aryl group, a heteroaryl group, a linear or branched alkyl group, an alkenyl group and a cycloalkyl group, wherein the aryl group, the heteroaryl group, the linear or branched alkyl group, the alkenyl group and the cycloalkyl group are unsubstituted or substituted by R7; R7 is selected from halogen, a C1-5 straight or branched alkyl group, a haloalkyl group, a C1-5 straight or branched alkoxy group and a nitro group. The compounds have good inhibitory activity against BRD4, HIV latent virus infection activation activity, low toxicity, high druggability and a more potential clinical application value.
