1082985-08-7

Basic information

• Product Name: C₁₂H₁₀F₅NO₂
• Synonyms: C₁₂H₁₀F₅NO₂
• CAS NO: 1082985-08-7
• Molecular Weight: 295.209
• Mol File: 1082985-08-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₀F₅NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₀F₅NO₂(1082985-08-7)
• EPA Substance Registry System: C₁₂H₁₀F₅NO₂(1082985-08-7)

Safety Data

• Hazardous Substances Data: 1082985-08-7(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 475-11-6 N-methyl-D-proline 
• 344-25-2 D-Prolin 

Relevant articles and documents

A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS

The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.

Cytotoxic simplified tubulysin analogues

An efficient route for the synthesis of the tubulysin family of antimitotic peptides was developed. Simplified tubulysin analogues were synthesized to define the minimum pharmacophore required for cytotoxicity. Simplified tubulysin analogues retain signif