1083-59-6 Usage
Structure
A pyrimidine derivative containing a furan ring with a nitro group attached
Usage
As a building block in the synthesis of various pharmaceuticals and chemical compounds
Potential applications
Antimicrobial and antifungal agent
Bioactivity
The presence of the nitro group makes it a potential candidate for reduction to form a nitroso compound, which can have biological significance as a bioactive molecule
Versatility
A versatile compound with potential applications in pharmaceutical and chemical industries
Check Digit Verification of cas no
The CAS Registry Mumber 1083-59-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,8 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1083-59:
(6*1)+(5*0)+(4*8)+(3*3)+(2*5)+(1*9)=66
66 % 10 = 6
So 1083-59-6 is a valid CAS Registry Number.
1083-59-6Relevant articles and documents
Chemotherapeutic nitroheterocycles. Antischistosomal properties of nitrofurylvinyl and nitrothienylvinyl heterocycles
Henry,Brown,Cory,et al.
, p. 1287 - 1291 (2007/10/05)
A series of 24 analogs of the experimental antischistosomal agent, 5 amino 3 [2 (5 nitro 2 furyl) vinyl] 1,2,4 oxadiazole, was prepared and evaluated in mice infected with Schistosoma mansoni. Although antischistosomal activity was widespread in the series, only four of the compounds showed significant curative properties. Compounds containing 2 imidazolyl and 2 pyridyl groups gave cure rates around 25% at 400 and 250 mg/kg dose levels, respectively. The 2 thiazolyl and 2 pyrimidyl derivatives were especially notable, yielding 100% cures at 250 and 200 mg/kg dose levels, respectively.
