108306-53-2 Usage
Uses
Used in Organic Synthesis:
4-BROMO-2-(TRIMETHYLSILYL)THIAZOLE is used as a building block in organic synthesis for the preparation of various complex organic molecules. Its unique structure and reactivity make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-BROMO-2-(TRIMETHYLSILYL)THIAZOLE is used as a reagent in the preparation of various drugs. Its ability to form stable intermediates and participate in key reactions allows for the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
4-BROMO-2-(TRIMETHYLSILYL)THIAZOLE is employed as a reagent in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique properties enable the development of new compounds with enhanced biological activity and selectivity, contributing to more effective and environmentally friendly agricultural practices.
Used in Materials Science:
In materials science, 4-BROMO-2-(TRIMETHYLSILYL)THIAZOLE is used as a reagent for the preparation of advanced materials with specific properties. Its incorporation into polymers, coatings, and other materials can lead to improved performance, such as enhanced stability, durability, or specific optical and electronic properties.
Used in Biomolecule Modification:
4-BROMO-2-(TRIMETHYLSILYL)THIAZOLE is used as a reagent for the modification of biomolecules, such as proteins, nucleic acids, and carbohydrates. Its ability to form covalent bonds with these biomolecules allows for the development of new conjugates with enhanced properties, such as improved stability, targeting, or activity.
Used in Fluorescent Dye Preparation:
4-BROMO-2-(TRIMETHYLSILYL)THIAZOLE is employed as a reagent in the preparation of thiazole-based fluorescent dyes. These dyes have applications in various fields, including bioimaging, sensing, and diagnostics, due to their unique optical properties and compatibility with biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 108306-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,3,0 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 108306-53:
(8*1)+(7*0)+(6*8)+(5*3)+(4*0)+(3*6)+(2*5)+(1*3)=102
102 % 10 = 2
So 108306-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H10BrNSSi/c1-10(2,3)6-8-5(7)4-9-6/h4H,1-3H3
108306-53-2Relevant academic research and scientific papers
Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for beta-secretase modulation
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Page/Page column 21, (2008/06/13)
The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles
NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
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Page/Page column 47-49, (2008/06/13)
The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating dyslipidemias. Pharmaceutical compositions and methods of use are also included.
HETEROCYCLIC COMPOUNDS
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Page/Page column 13, (2008/06/13)
Compounds of formula I : and pharmaceutically-acceptable salts thereof, wherein Ar and R are as defined in the specification, compositions containing such compounds and the use of such compounds and compositions for use in therapy.
Synthesis of (Trimethylsilyl)thiazoles and Reactions with Carbonyl Compounds. Selectivity Aspects and Synthetic Utility
Dondoni, Alessandro,Fantin, Giancarlo,Fogagnolo, Marco,Medici, Alessandro,Pedrini, Paola
, p. 1748 - 1761 (2007/10/02)
Synthetic routes to all possible regioisomeric mono- and bis(trimethylsilyl)thiazoles as well as to the tris(trimethylsilyl) derivative via lithiation-silylation sequences of the thiazole ring followed by selective protodesilylation in some cases are described. (Trimethylsilyl)thiazoles serve as thiazolyl donor synthons upon reaction with carbonyl compounds (ketenes, acyl chlorides, aldehydes) for the preparation of mono- and bis-substituted thiazoles in very good yields.Carbodesilylation occurs more readily at the 2- than 5-position, whereas no reaction takes place at the 4-position.A mechanism via a thiazolium 2-ylide as an intermediate is suggested for the carbodesilylation at the 2-position.
Synthesis of Stannylthiazoles and Mixed Stannylsilylthiazoles and their Use for a Convenient Preparation of Mono- and Bis-halothiazoles
Dondoni, A.,Mastellari, A. R.,Medici, A.,Negrini, E.,Pedrini, P.
, p. 757 - 760 (2007/10/02)
Stannylthiazoles and stannyl-silylthiazoles have been prepared and employed as thiazolyl carbanion equivalents in reactions with halogens to give mono- and mixed bis-halothiazoles in good yields.
