1083094-27-2Relevant academic research and scientific papers
From cyclopropenes to tetrasubstituted furans: Tandem isomerization/ alkenylation sequence with Cu/Pd relay catalysis
Song, Chuanling,Ju, Lin,Wang, Mingchao,Liu, Pengcheng,Zhang, Yuanzhe,Wang, Jianwu,Xu, Zhenghu
, p. 3584 - 3589 (2013)
Pon de relay: A convenient and efficient synthesis of alkene-functionalized furans from cyclopropenes, which proceeds through an isomerization/olefination cascade sequence under copper-palladium relay catalysis, has been developed (see scheme). Copyright
Azide Radical Initiated Ring Opening of Cyclopropenes Leading to Alkenyl Nitriles and Polycyclic Aromatic Compounds
Muriel, Bastian,Waser, Jerome
supporting information, p. 4075 - 4079 (2021/01/18)
We report herein a radical-mediated amination of cyclopropenes. The transformation proceeds through a cleavage of the three-membered ring after the addition of an azide radical on the strained double bond and leads to tetrasubstituted alkenyl nitrile derivatives upon loss of N2. With 1,2-diaryl substituted cyclopropenes, this methodology could be extended to a one-pot synthesis of highly functionalized polycyclic aromatic compounds (PACs). This transformation allows the synthesis of nitrile-substituted alkenes and aromatic compounds from rapidly accessed cyclopropenes using only commercially available reagents.
Stereoselective synthesis of tri- and tetrasubstituted alkenes by iron-catalyzed carbometalation ring-opening reactions of cyclopropenes
Wang, Yi,Fordyce, Euan A. F.,Chen, Fung Yan,Lam, Hon Wai
supporting information; experimental part, p. 7350 - 7353 (2009/04/10)
(Chemical Equation Presented) Open sesame: An iron-catalyzed cyclopropene carbometalation ring-opening sequence using trialkylaluminum reagents is described. The reactions proceed with high levels of regio- and stereo-control to provide a range of multisubstituted alkenes, including trisubstituted vinylsilanes, trisubstituted vinylstannanes, and all-carbon tetrasubstituted alkenes.
