108310-79-8 Usage
General Description
Thiazolo[5,4-c]pyridin-2-amine, also known as TPA, is a chemical compound with the formula C7H6N4S. It belongs to the thiazole class of compounds and contains a pyridine ring and an amine group, making it a heterocyclic amine. TPA is often used as a building block in organic synthesis and drug discovery due to its versatile reactivity and potential pharmacological properties. It is also a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. TPA has been studied for its potential antitumor and antiviral activities, and it continues to be of interest in medicinal chemistry research.
Check Digit Verification of cas no
The CAS Registry Mumber 108310-79-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,3,1 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 108310-79:
(8*1)+(7*0)+(6*8)+(5*3)+(4*1)+(3*0)+(2*7)+(1*9)=98
98 % 10 = 8
So 108310-79-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H5N3S/c7-6-9-4-1-2-8-3-5(4)10-6/h1-3H,(H2,7,9)
108310-79-8Relevant articles and documents
Iodine-catalyzed amination of benzothiazoles with KSeCN in water to access primary 2-aminobenzothiazoles
Zhu, Yu-Shen,Shi, Linlin,Fu, Lianrong,Chen, Xiran,Zhu, Xinju,Hao, Xin-Qi,Song, Mao-Ping
supporting information, p. 1497 - 1500 (2021/09/09)
A facile and sustainable approach for the amination of benzothiazoles with KSeCN using iodine as the catalyst in water has been disclosed under transition-metal free conditions. The reaction proceeded smoothly to afford various primary 2-amino benzothiazoles in up to 96% yield. A series of control experiments were performed, suggesting a ring-opening mechanism was involved via a radical process. This protocol provides efficient synthesis of primary 2-aminobenzothiazoles
