1083169-87-2

Upstream product

• 6307-83-1 3-bromo-5-nitro-benzoic acid 
• 51339-40-3 3-bromo-5-nitrobenzoyl chloride 
• 1083169-86-1 3-bromo-5-nitro-N-(2-(pyrrolidin-1-yl)ethyl)benzamide 

Downstream Products

• 1083169-93-0 3-bromo-5-(4-(3-(but-3-enyloxy)phenyl)pyrimidin-2-ylamino)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide 

Relevant academic research and scientific papers

PYRIMIDINE DERIVATIVES

The present invention relates to pyrimidine compounds that are useful as agents for the treatment of kinase related disorders such as proliferative disorders. More particularly, the present invention relates to substituted pyrimidine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative disorders. These compounds may be useful as medicaments for the treatment of a number of kinase related disorders such as proliferative disorders including tumours and cancers as well as other disorders or conditions related to or associated with kinases.