1083181-22-9 Usage
Uses
Used in Peptide Synthesis:
(trans)-2-[(tert-butoxy)carbonyl]aminocyclopropane-1-carboxylic acid is used as a building block in peptide synthesis for its ability to protect the amino group during the synthesis process. The tert-butoxy carbonyl group can be selectively removed, allowing for the controlled formation of peptide bonds and the synthesis of complex peptide structures.
Used in Amino Acid Synthesis:
In amino acid synthesis, (trans)-2-[(tert-butoxy)carbonyl]aminocyclopropane-1-carboxylic acid serves as a protected intermediate, facilitating the introduction of the amino group into various organic molecules. The cyclopropane ring provides a stable and rigid scaffold, which can be beneficial for the synthesis of specific amino acid derivatives.
Used in Medicinal Chemistry:
(trans)-2-[(tert-butoxy)carbonyl]aminocyclopropane-1-carboxylic acid is utilized in medicinal chemistry for the development of novel drug candidates. Its unique structure and the ability to stabilize peptide conformations make it a valuable component in the design of bioactive peptides and peptidomimetics with potential therapeutic applications.
Used in Organic Synthesis and Chemical Research:
In the broader field of organic synthesis and chemical research, (trans)-2-[(tert-butoxy)carbonyl]aminocyclopropane-1-carboxylic acid is employed as a versatile reagent and intermediate. Its cyclopropane ring and protecting group chemistry offer opportunities for the exploration of new synthetic pathways and the development of innovative chemical transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 1083181-22-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,3,1,8 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1083181-22:
(9*1)+(8*0)+(7*8)+(6*3)+(5*1)+(4*8)+(3*1)+(2*2)+(1*2)=129
129 % 10 = 9
So 1083181-22-9 is a valid CAS Registry Number.
1083181-22-9Relevant academic research and scientific papers
Trans-2-amino-cyclopropyl formic acid derivative and synthetic method thereof
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Paragraph 0205; 0206; 0211; 0212, (2017/01/26)
The invention discloses a trans-2-amino-cyclopropyl formic acid derivative and a synthetic method thereof. The synthetic method includes the following steps that a compound II is used as a raw material and reacts with di-tert-butyl dicarbonate under the alkaline condition to prepare a compound III; the compound III and alkaline are subjected to hydrolysis reaction to obtain a compound IV; the compound IV and trifluoroacetic acid react for deprotection to prepare a compound I. The synthetic method of trans-2-amino-cyclopropyl formic acid derivative includes three-step reaction, is short in route, low in cost, high in yield, easy to prepare on a large scale and capable of keeping stability of a three-membered ring, and the total yield can reach 90.92%.
