108388-36-9

Upstream product

• 109-92-2 ethyl vinyl ether 
• 105-13-5 4-Methoxybenzyl alcohol 
• 74-86-2 acetylene 
• 111-34-2 -butyl vinyl ether 
• 108-05-4 vinyl acetate 

Downstream Products

• 213548-34-6 2'-O-[1-(4-methoxybenzyloxy)ethyl]-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 334868-02-9 4,5-dihydro-5-[(4-methoxybenzyl)oxy]-3-(3-pyridylmethyl)isoxazolium-2-olate 

Relevant academic research and scientific papers

N,N-Dimethylformamide-stabilised palladium nanoparticles combined with bathophenanthroline as catalyst for transfer vinylation of alcohols from vinyl ether

We reportN,N-dimethylformamide-stabilised Pd nanoparticle (Pd NP)-catalysed transfer vinylation of alcohols from vinyl ether. Pd NPs combined with bathophenanthroline exhibited high catalytic activity. This reaction proceeded with low catalyst loading and the catalyst remained effective even after many rounds of recycling. The observation of the catalyst using transmission electron microscopy and dynamic light scattering implied no deleterious aggregation of Pd NPs.

Vinyl polymerization versus [1,3] O to C rearrangement in the ruthenium-catalyzed reactions of vinyl ethers with hydrosilanes

Two reactions, vinyl polymerization and [1,3] O to C rearrangement of vinyl ethers, are investigated in the ruthenium-catalyzed reaction with hydrosilanes. The reaction pathways are dependent on the substituents of the vinyl ether, in particular, those of the alkoxy group. Primary-, secondary-, and tertiary-alkyl vinyl ethers, ROCHCH2, are polymerized with ease to give the corresponding polymer in good yields. When R is electron-donating benzyl groups, the reaction does not give the polyvinyl ether but results in [1,3] O to C rearrangement to give the corresponding aldehyde, RCH2CHO in moderate to good yields. The rearrangement selectively proceeds when vinyl ethers having α-substituents are used as the starting materials to give the corresponding ketones in high yields. With catalytic amounts of hydrosilanes, the rearrangement gives ketones or aldehydes selectively. In sharp contrast, use of excess amounts of hydrosilanes leads to the rearrangement followed by reduction of the formed carbonyl group to give the corresponding silyl ethers in good yields. Nature of catalytically active species is discussed. Crown Copyright

Construction of substituted benzene rings by palladium-catalyzed direct cross-coupling of olefins: A rapid synthetic route to 1,4-naphthoquinone and its derivatives

Ring the changes: The direct cross-coupling of electron-deficient 1,4-benzoquinone or its derivatives with electron-rich alkyl vinyl ethers proceeds in a tandem manner to produce substituted benzene rings with good selectivity and in good to excellent yields (see scheme). The reaction has the potential for the rapid synthesis of diverse substituted benzene rings as it is not limited by substituent effects. Copyright

Enantioselective preparation of 8-oxabicyclo[3.2.1]octane derivatives via asymmetric [3+2]-cycloaddition of platinum-containing carbonyl ylides with vinyl ethers

A catalytic asymmetric synthesis of 8-oxabicyclo[3.2.1]octane derivatives was achieved through the [3+2]-cycloaddition of the platinum-containing carbonyl ylides generated from acyclic γ,δ-ynones on treatment with 10 mol % of PtCl2-Walphos and

Novel five/five- and six/five-membered bicyclic nitroso acetals from high-pressure-promoted cyclisation reactions of p-methoxybenzyl vinyl ether, 1-nitro-2-heteroaryl ethenes, and mono- and di-substituted olefins

At 15 kbar the 1-nitro-2-heteroarylethenes 2a-c reacted in a one-pot three-component cycloaddition with p-methoxybenzyl vinyl ether (1) and methyl acrylate to yield novel heteroaromatic-substituted six/five-membered bicyclic nitroso acetals. In the reacti

Acetals as New 2′-O-Protecting Functions for the Synthesis of Oligoribonucleotides: Synthesis of Uridine Building Blocks and Evaluation of Their Relative Acid Stability

A broad variety of new acyclic vinyl ethers (see 6-41) have been synthesized via the vinyl-interchange reaction of ethyl vinyl ether at room temperature using mercury(II) trifluoroacetate as a highly efficient catalyst. The appropriate vinyl ethers were r