108397-75-7

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 2,4,6-trimethyl- (9CI)
• Synonyms: 5-Pyrimidinecarboxylic acid, 2,4,6-trimethyl- (9CI)
• CAS NO: 108397-75-7
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• Product Categories: PYRIMIDINE
• Mol File: 108397-75-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 308.5±37.0 °C(Predicted)
• Appearance: /
• Density: 1.210±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 1.04±0.38(Predicted)
• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 2,4,6-trimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 2,4,6-trimethyl- (9CI)(108397-75-7)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 2,4,6-trimethyl- (9CI)(108397-75-7)

Safety Data

• Hazardous Substances Data: 108397-75-7(Hazardous Substances Data)

Usage

General Description

5-Pyrimidinecarboxylic acid, 2,4,6-trimethyl- (9CI) is a chemical compound with the molecular formula C9H10N2O2. It is also known as trimethylpyrimidin-2,4,6-trione and is a derivative of pyrimidine. 5-Pyrimidinecarboxylic acid, 2,4,6-trimethyl- (9CI) has a pyrimidine ring with three methyl groups attached to different positions. It is used in the synthesis of pharmaceuticals and agrochemicals. The compound has potential applications in the development of new drugs and as a building block in organic chemistry. It is important to handle this chemical with care as it may be hazardous if not used properly.

Upstream product

• 90905-54-7 ethyl 2,4,6‐trimethylpyrimidine‐5‐carboxylate 
• 544704-03-2 2,4,6-trimethyl-pyrimidine-5-carboxylic acid tert-butyl ester 
• 91179-57-6 tert-butyl 2-acetyl-3-oxobutanoate 
• 603-69-0 ethyl 2-acetylacetoacetate 
• 544704-01-0 2-acetyl-3-methoxy-but-2-enoic acid tert-butyl ester 
• 108169-16-0 5-(methoxycarbonyl)-2,3,6-trimethylpyrimidine 

Downstream Products

• 306296-03-7 C₃₄H₄₂F₃N₅O₂ 
• 306295-97-6 C₃₄H₄₂F₃N₅O 
• 544704-14-5 (4-Methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-(2,4,6-trimethyl-pyrimidin-5-yl)-methanone 

Relevant articles and documents

PROCESS FOR THE PREPARATION AND PURIFICATION OF 2-(ALKOXYALKYLIDENE)-3-KETOALKANOIC ACID ESTERS FROM 3-KETOALKANOIC ACID ESTERS

In its several embodiments, this invention discloses a novel process to prepare the compounds of Formula 3, wherein R1 is lower alkyl, and R2 and R3 can be the same or different, each being independently selected from the group consisting of alkyl, aryl a

Oximino-piperidino-piperidine-based CCR5 antagonists. Part 2: Synthesis, SAR and biological evaluation of symmetrical heteroaryl carboxamides

The synthesis, SAR and biological evaluation of symmetrical amide analogues of our clinical candidate SCH 351125 are described. A series of potent and orally bioavailable CCR5 antagonists containing symmetrical 2,6-dimethyl isonicotinamides and 2, 6-dimethyl pyrimidines amides were generated with enhanced affinity for the CCR5 receptor.