603-69-0

Basic information

• Product Name: Ethyl diacetoacetate
• Synonyms: Acetoacetic acid, 2-acetyl-, ethyl ester;Butanoic acid, 2-acetyl-3-oxo-, ethyl ester;Ethyl 2-acetyl-3-oxobutanoate;Ethyl 2-acetylacetoacetate;DIACETOACETIC ACID ETHYL ESTER;ETHYL 2-ACETYL-3-OXOBUTYRATE;ETHYL DIACETOACETATE;ETHYL DIACETYL ACETATE
• CAS NO: 603-69-0
• Molecular Formula: C₈H₁₂O₄
• Molecular Weight: 172.18
• EINECS: 210-053-3
• Product Categories: Pharmaceutical Intermediates;Acetics acid and esters;C8 to C9;Carbonyl Compounds;Esters
• Mol File: 603-69-0.mol

Chemical Properties

• Boiling Point: 104-105 °C17 mm Hg(lit.)
• Flash Point: 185 °F
• Appearance: clear colorless to yellow liquid
• Density: 1.104 g/mL at 25 °C(lit.)
• Vapor Pressure: 8.24E-06mmHg at 25°C
• Refractive Index: n20/D 1.47(lit.)
• PKA: 6.93±0.46(Predicted)
• Water Solubility: Not miscible in water.
• BRN: 775014
• CAS DataBase Reference: Ethyl diacetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl diacetoacetate(603-69-0)
• EPA Substance Registry System: Ethyl diacetoacetate(603-69-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• WGK Germany: 3
• Hazardous Substances Data: 603-69-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Ethyl diacetoacetate is used as a key intermediate for the synthesis of various organic compounds. Its reactivity and functional groups allow it to be easily modified and incorporated into more complex molecules, facilitating the creation of a diverse array of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethyl diacetoacetate is used as a starting material for the production of various drugs and pharmaceutical agents. Its ability to be readily transformed into other compounds makes it a valuable component in the development of new medications and therapies.
Used in Agrochemicals:
Ethyl diacetoacetate is also utilized in the agrochemical sector, where it serves as a precursor for the synthesis of various agrochemical products. Its involvement in the production of these compounds contributes to the development of effective solutions for agricultural applications.
Used in Dye Industry:
In the dye industry, Ethyl diacetoacetate is employed in the preparation of specific dyes, such as 3-acetyl-6-chloro-7-hydroxy-4-methylcoumarin. Its role in the synthesis of these dyes highlights its versatility and importance in the production of colorants for various applications.

InChI:InChI=1/C8H12O4/c1-4-12-8(11)7(5(2)9)6(3)10/h11H,4H2,1-3H3

Upstream product

• 29214-62-8 3-acetoxy-crotonic acid ethyl ester 
• 108-24-7 acetic anhydride 
• 141-97-9 ethyl acetoacetate 
• 60-29-7 diethyl ether 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 67-66-3 chloroform 
• 75-36-5 acetyl chloride 
• 71-43-2 benzene 
• 123-91-1 1,4-dioxane 
• 99181-91-6 ethyl 2-acetyl-3-ethoxybut-2-enoate 
• 7705-08-0 iron(III) chloride 
• 7637-07-2 boron trifluoride 
• 107-06-2 1,2-dichloro-ethane 
• 141-78-6 ethyl acetate 

Downstream Products

• 6622-92-0 4-hydroxy 2,6-dimethylpyrimidine 
• 108-26-9 3-methyl-2-pyrazoline-5-one 
• 141-97-9 ethyl acetoacetate 
• 64-19-7 acetic acid 
• 203587-54-6 5,7-Dimethyl-2-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester 
• 89193-18-0 3,5-dimethyl-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 35691-93-1 3,5-Dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 1068-57-1 acetic acid hydrazide 
• 2436-79-5 diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate 
• 75163-04-1 N-benzoyl-O-(1-carbethoxy-1-acetylisopropenyl)urethan 
• 91614-62-9 2-acetyl-3-methyl-7-phenylpyrazolo<1,2-a>pyrazole-1,5(1H,5H)-dione 
• 91614-67-4 2-acetyl-3-methyl-5-phenylpyrazolo<1,2-a>pyrazole-1,7(1H,7H)-dione 
• 103409-93-4 ethyl 1-(4-tolyl)-3,5-dimethylpyrazole-4-carboxylate 

Relevant articles and documents

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