108418-33-3

Basic information

• Product Name: Isoxazole, 5-ethyl-3-methyl-4-nitro- (9CI)
• Synonyms: Isoxazole, 5-ethyl-3-methyl-4-nitro- (9CI)
• CAS NO: 108418-33-3
• Molecular Formula: C6H8N2O3
• Molecular Weight: 156.13932
• Product Categories: OXAZOLE
• Mol File: 108418-33-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isoxazole, 5-ethyl-3-methyl-4-nitro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazole, 5-ethyl-3-methyl-4-nitro- (9CI)(108418-33-3)
• EPA Substance Registry System: Isoxazole, 5-ethyl-3-methyl-4-nitro- (9CI)(108418-33-3)

Safety Data

• Hazardous Substances Data: 108418-33-3(Hazardous Substances Data)

Upstream product

• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 31301-34-5 3-methyl-5-ethylisoxazole 

Downstream Products

• 225094-34-8 3-methyl-5-ethyl-4-aminoisoxazole 

Relevant articles and documents

Flash Vacuum Pyrolysis of Some 4-Nitroisoxasoles

Flash vacuum pyrolysis (FVP) of some 5-alkyl-3-methyl-4-nitroisoxasoles affords 1-nitro-1-cyanoacetone as the only product.A general mechanism is suggested which involves isomerization of the isoxazole to a 1-azirine.A nonclassical reaction of 3-methyl-4-nitroisoxazoles is assumed as a consequence of the electron-withdrawing ability of the nitro group, which precludes ring closure of the nitrile ylide intermediate to the oxazole isomer.The formation of 1-nitro-1-cyanoacetone by FVP of the 3-unsubstituted 5-methyl-4-nitroisoxazole suggests that the activation barrier for a 1,2-hydrogen shift from a 1-azirine or vinylnitrene is lower than that for the formation of nitrile ylide.The FVP of 5-ethyl-3-methylisoxzaole affords 5-ethyl-2-methyloxazole.