108429-38-5Relevant articles and documents
α CETOPHOSPHONATES ET ESTERS CYCLIQUES D'HYDROXYMETHYLENES DIPHOSPHONATES SYNTHESES, STRUCTURES ET HYDROLYSE
Tromelin, Anne,El Manouni, Driss,Burgada, R.
, p. 301 - 312 (2007/10/02)
Synthesis of symmetrical diesters derived from hydroxy methylene diphosphonic acids 1 to 8 is described either in one step or via the corresponding α ketophosphonate 1a to 8a.Study of the diphosphonates (1 to 6) -> phosphate-phosphonates (1b to 6b) isomerization has been realized.Results related to peculiar cases in connection with nonsymmetrical esters 10, 11, 17 and study of the hydrolysis reaction of diphosphonates are presented.