108441-91-4

Basic information

• Product Name: 1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentafuranosyl)-5-trifluoromethyluracil
• CAS NO: 108441-91-4
• Molecular Weight: 616.615
• Mol File: 108441-91-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentafuranosyl)-5-trifluoromethyluracil(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentafuranosyl)-5-trifluoromethyluracil(108441-91-4)
• EPA Substance Registry System: 1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentafuranosyl)-5-trifluoromethyluracil(108441-91-4)

Safety Data

• Hazardous Substances Data: 108441-91-4(Hazardous Substances Data)

Upstream product

• 70-00-8 2'-deoxy-5-trifluoromethyluridine 
• 76-83-5 trityl chloride 
• 23186-41-6 C₂₉H₂₅F₃N₂O₅ 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1356822-11-1 1-(2,3-dideoxy-3-fluoro-5-O-trityl-β-D-erythro-pentofuranosyl)-5-trifluoromethyluracil 
• 1251063-85-0 1-(5-O-trityl-2-deoxy-β-D-lyxofuranosyl)-5-trifluoromethyluracil 

Relevant articles and documents

Antimycobacterial activities of 5-alkyl (or halo)-3′-substituted pyrimidine nucleoside analogs

Several 5-alkyl (or halo)-3′-azido (amino or halo) analogs of pyrimidine nucleosides have been synthesized and evaluated against Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium. Among these compounds, 3′-azido-5-ethyl-2′,3′-dideoxyuridine (3) was found to have significant antimycobacterial activities against M. bovis (MIC 50 = 1 μg/mL), M. tuberculosis (MIC50 = 10 μg/mL) and M. avium (MIC50 = 10 μg/mL).