108462-77-7

Upstream product

• 627-19-0 1-Pentyne 
• 100-07-2 4-methoxy-benzoyl chloride 
• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 

Downstream Products

• 62596-42-3 2-Ethyl-5-(4-methoxy-phenyl)-furan 
• 1018459-62-5 (4-methoxyphenyl)[5-n-propyl-3-(thiophen-2-yl)isoxazol-4-yl]methanone 
• 1219617-96-5 3-(diphenylmethyleneamino)-6-(4-methoxyphenyl)-4-propyl-2H-pyran-2-one 
• 1321625-36-8 3-(4-bromobenzoyl)-6-(4-methoxyphenyl)-4-propyl-2H-pyran-2-one 
• 1321625-18-6 3-acetyl-6-(4-methoxyphenyl)-4-propyl-2H-pyran-2-one 

Relevant academic research and scientific papers

Carbonylative Sonogashira Coupling of Aryl Iodides with Terminal Alkynes Catalyzed by Palladium Nanoparticles

A convenient and efficient method for the synthesis of α,β-alkynyl ketones from the three-component coupling of aryl iodides, terminal alkynes, and carbon monoxide (carbonylative Sonogashira coupling reaction) is successfully developed. The carbonylative Sonogashira coupling reaction proceeded smoothly under mild conditions in the presence of palladium nanoparticles to produce the corresponding α,β-alkynyl ketones in good to excellent yields.

Synthesis of ynones via recyclable polystyrene-supported palladium(0) complex catalyzed acylation of terminal alkynes with acyl chlorides under copper- and solvent-free conditions

Herein, a highly efficient method for the copper- and solvent-free coupling reaction of acyl chlorides and terminal alkynes catalyzed by 1-phenyl-1,2-propanedione-2-oxime thiosemicarbazone-functionalized polystyrene resin-supported Pd(0) complex is descri

Novel microwave-assisted one-pot synthesis of isoxazoles by a three-component coupling-cycloaddition sequence

The consecutive Sonogashira coupling of acid chlorides with terminal alkynes, followed by 1,3-dipolar cycloaddition under dielectric heating of in situ generated nitrile oxides from hydroximinoyl chlorides furnishes isoxazoles in moderate to good yields i