108462-85-7Relevant academic research and scientific papers
Preparation of 2,5-disubstituted furans from terminal ynones and aldehydes with CrCl2, Me3SiCl, and H2O
Takai,Morita,Sakamoto
, p. 1614 - 1616 (2001)
Treatment of α,β-acetylenic ketones with chromium(II) in the presence of aldehydes, Me3SiCl and water in THF gives 2,5-disubstituted furans in good to excellent yields.
A highly efficient synthesis of 2,5-disubstituted furans from enyne acetates catalyzed by lewis acid and palladium
Chen, Zheng-Wang,Luo, Miao-Ting,Wen, Yue-Lu,Ye, Min,Zhou, Zhong-Gao,Liu, Liang-Xian
supporting information, p. 2341 - 2344 (2015/08/06)
A highly efficient synthesis of a wide range of 2,5-disubstituted furans from enyne acetates is described. The reactions are conducted by using Lewis acid and palladium catalyst and provide symmetrical and unsymmetrical products in good to excellent yields, with broad substrate scope, including a variety of aromatic and aliphatic substituents in the 2- and 5-position of the furan ring.
An extremely facile synthesis of furans, pyrroles, and thiophenes by the dehydrative cyclization of propargyl alcohols
Aponick, Aaron,Li, Chuan-Ying,Malinge, Jeremy,Marques, Emerson Finco
supporting information; experimental part, p. 4624 - 4627 (2009/12/09)
Furans, pyrroles, and thiophenes are efficiently prepared by gold-catalyzed dehydrative cyclizations of readily available, heteroatom-substituted propargyllc alcohols. The reactions are rapid, high-yielding, and procedurally simple, giving essentially pure aromatic heterocycles In minutes under open-flask conditions with catalyst loadings as low as 0.05 mol %.
A NOVEL PALLADIUM-CATALYZED REARRANGEMENT OF ACETYLENIC KETONES TO FURANS
Sheng, Huaiyu,Lin, Shouyuan,Huang, Yaozeng
, p. 4893 - 4894 (2007/10/02)
A novel rearrangement of 1-aryl-4-alkyl-2-butyn-1-one in the presence of Pd(dba)2-PPh3 catalyst gave 2,4-substituted furans in moderate yields.
