1084926-95-3Relevant academic research and scientific papers
An efficient reduction protocol for the synthesis of β-hydroxycarbamates from β-nitro alcohols in one pot: a facile synthesis of (-)-β-conhydrine
Saikia, Partha Pratim,Baishya, Gakul,Goswami, Abhishek,Barua, Nabin C.
scheme or table, p. 6508 - 6511 (2009/04/06)
An efficient and practical one-pot protocol for the reduction of β-nitro alcohols to their corresponding N-(tert-butoxycarbonyl) amino alcohols using Zn-NH4Cl in aqueous methanol is described. Other reducible groups such as ketones and isolated double bonds remained intact. This methodology allows a short synthesis of (-)-β-conhydrine to be achieved.
