1084953-67-2Relevant articles and documents
Convenient modular construction of medicinally important 5-acylamino-4,5-dihydroisoxazoles featuring four elements of diversity
Kulyashova, Alexandra,Krasavin, Mikhail
, p. 4395 - 4397 (2016)
An efficient modular approach toward medicinally important 5-acylamino-4,5-isoxazolines via the 1,3-dipolar cycloaddition reaction of nitrile oxides and MCR-derived enamide building blocks is described. This approach results in isoxazolines containing four elements of diversity utilizing two practically simple synthetic operations.
A method for cleaving an allyl protecting group at the amide nitrogen of peptides by one-pot olefin isomerization-oxidation
Kajihara, Kouki,Arisawa, Mitsuhiro,Shuto, Satoshi
supporting information; experimental part, p. 9494 - 9496 (2009/04/06)
(Chemical Equation Presented) A facile method for N-deallylation at the amide nitrogen of peptides is described. One-pot deallylation of a substrate through ruthenium hydride-catalyzed terminal olefin isomerization and subsequent ozonolysis gave the corresponding deallylated product under mild conditions.