1084953-75-2Relevant academic research and scientific papers
A method for cleaving an allyl protecting group at the amide nitrogen of peptides by one-pot olefin isomerization-oxidation
Kajihara, Kouki,Arisawa, Mitsuhiro,Shuto, Satoshi
supporting information; experimental part, p. 9494 - 9496 (2009/04/06)
(Chemical Equation Presented) A facile method for N-deallylation at the amide nitrogen of peptides is described. One-pot deallylation of a substrate through ruthenium hydride-catalyzed terminal olefin isomerization and subsequent ozonolysis gave the corresponding deallylated product under mild conditions.
