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108498-50-6

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108498-50-6 Usage

Chemical class

Sulfinyl acetamide derivative

Explanation

The compound contains a sulfinyl group (R2S) bonded to an acetamide group.

Explanation

The compound has a furan-2-ylmethyl group attached to a sulfur atom and a piperidin-1-ylmethyl group attached to a phenoxypropyl chain.

Explanation

The sulfur atom in the compound is connected to both a furan ring and a piperidine ring, which are key structural features.

Explanation

The acetamide group is part of the compound and is connected to a phenoxypropyl chain, which may contribute to its bioactive properties.
5. Potential pharmaceutical applications

Explanation

Due to its structural features, the compound may have bioactive properties and could be explored for its pharmacological effects or as a lead compound for drug development.
6. Further research and testing required

Explanation

To determine the specific therapeutic potential of the compound, additional research and testing would be necessary.

Functional groups

Furan-2-ylmethyl and piperidin-1-ylmethyl

Chemical structure

Sulfur atom bonded to a furan ring and a piperidine ring

Acetamide group

Attached to a phenoxypropyl chain

Check Digit Verification of cas no

The CAS Registry Mumber 108498-50-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,4,9 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 108498-50:
(8*1)+(7*0)+(6*8)+(5*4)+(4*9)+(3*8)+(2*5)+(1*0)=146
146 % 10 = 6
So 108498-50-6 is a valid CAS Registry Number.

108498-50-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(furan-2-ylmethylsulfinyl)-N-[3-[3-(piperidin-1-ylmethyl)phenoxy]propyl]acetamide

1.2 Other means of identification

Product number -
Other names Frg 8701

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:108498-50-6 SDS

108498-50-6Downstream Products

108498-50-6Relevant articles and documents

A novel histamine 2(H2) receptor antagonist with gastroprotective activity. I. Synthesis and pharmacological evaluation of N- phenoxypropylacetamide derivatives with thioether function

Sekine, Yasuo,Hirakawa, Nobuhiko,Kashiwaba, Noriaki,Matsumoto, Hajime,Kutsuma, Teruo,Yamaura, Tetsuaki,Sekine, Akihiro

, p. 610 - 615 (2007/10/03)

In an attempt to develop new types of anti-ulcer agents, a series of N- (phenoxypropyl)acetamide derivatives with a thioether moiety and their sulfur-oxidized analogues were synthesized and evaluated for histamine H2- receptor antagonistic activity, Ca antagonistic activity and gastric anti- secretory activity in the lumen-perfuseed rat. Selected compounds were also tested for gastroprotective activity, which was expected to be based on Ca antagonistic activity. Structure-activity relationships are discussed. As a thioether moiety, -CH2-S(O)p-CH2-Ar (Ar; phenyl or furyl) was found to be optimal for the above activities. Especially, N-[3-[(3-(piperidinomethyl) phenoxy]propyl]acetamide with a benzyl sulfinyl, benzylsulfonyl, furfurylsulfinyl or furfuryisulfonyl group showed potent gastroprotective activity upon oral administration in a rat model. These compounds are candidates for novel anti-ulcer drugs with gastric anti-secretory and gastroprotective activities. 2-Furfurylsulfinyl-N-[3- [(piperidinomethyl)phenoxy]propyl]-acetamide was the most potent among the compounds tested and was given the code designation FRG-8701.

ALKYLAMIDE DERIVATIVES WITH H2-RECEPTOR ANTAGONISTIC AND CYTOPROTECTIVE ACTION

-

, (2008/06/13)

Alkylamide derivatives having the formula, These compounds have a strong antiulcer action depend on histamine H 2-receptor antagonistic action and a cytoprotective action upon gastric mucous membrance.

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