108521-49-9Relevant academic research and scientific papers
A facile direct conversion of aldehydes to esters and amides using acetone cyanohydrin
Raj, I. Victor Paul,Sudalai
, p. 8303 - 8306 (2005)
Aromatic aldehydes with electron-withdrawing groups undergo rapid reactions with a variety of alcohols and secondary amines to afford the corresponding esters and amides, respectively, in high yields, when treated with NaCN or acetone cyanohydrin and base under ambient reaction conditions. In case of α,β-unsaturated aldehydes, simultaneous reduction of the CC bond along with esterification occurred to produce the saturated esters in high yields.
Divergent Elementoboration: 1,3-Haloboration versus 1,1-Carboboration of Propargyl Esters
Wilkins, Lewis C.,Soltani, Yashar,Lawson, James R.,Slater, Ben,Melen, Rebecca L.
supporting information, p. 7364 - 7368 (2018/05/03)
This work showcases the 1,3-haloboration reaction of alkynes in which boron and chlorine add to propargyl systems in a proposed sequential oxazoliumborate formation with subsequent ring-opening and chloride migration. In addition, the functionalization of
Transition-metal-free aerobic oxidative cleavage of C-C bonds in α-hydroxy ketones and mechanistic insight to the reaction pathway
Liu, Hui,Dong, Chao,Zhang, Zeguang,Wu, Peiyu,Jiang, Xuefeng
supporting information, p. 12570 - 12574 (2013/02/22)
Clear cut: For the title reaction, O2, the ideal oxidant, was used as the only oxidizing reagent. The dimer intermediate (see scheme) and isotopic labeling control experiments with 18O2 partially disclosed the reaction mec
A simple procedure for the esterification of alcohols with sodium carboxylate salts using 1-tosylimidazole (TsIm)
Soltani Rad, Mohammad Navid,Behrouz, Somayeh,Faghihi, Mohammad Ali,Khalafi-Nezhad, Ali
, p. 1115 - 1120 (2008/09/17)
An efficient and selective method for esterification of alcohols using N-(p-toluenesulfonyl)imidazole (TsIm) is described. In this method, alcohols are refluxed with a mixture of RCO2Na (R: alkyl and aryl), TsIm, and triethylamine in the presence of catalytic amounts of tetra-n-butylammonium iodide (TBAI) in DMF to afford the corresponding esters in good yields. This methodology is highly efficient for various structurally diverse alcohols with selectivity for ROH: 1° > 2° > 3°.
