72802-41-6

Basic information

• Product Name: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE
• Synonyms: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE;2-Hydroxy-1-(3-nitro-phenyl)-ethanone
• CAS NO: 72802-41-6
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.15
• Mol File: 72802-41-6.mol

Chemical Properties

• Melting Point: 88-90°C
• Boiling Point: 297°C at 760 mmHg
• Flash Point: 131.9°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 0.000624mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE(72802-41-6)
• EPA Substance Registry System: 2-HYDROXY-1-(3-NITROPHENYL)-1-ETHANONE(72802-41-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 72802-41-6(Hazardous Substances Data)

Usage

Uses

2-Hydroxy-1-(3-nitrophenyl)-1-ethanone is used as a chemical intermediate for [application reason] in the chemical industry.
2-Hydroxy-1-(3-nitrophenyl)-1-ethanone is used as a research compound for [application reason] in scientific studies.
(Note: Since the provided materials do not specify the exact uses of 2-Hydroxy-1-(3-nitrophenyl)-1-ethanone, the above uses are hypothetical and should be replaced with actual applications once they are identified.)

InChI:InChI=1/C8H7NO4/c10-5-8(11)6-2-1-3-7(4-6)9(12)13/h1-4,10H,5H2

Upstream product

• 92554-40-0 α-tosyloxy-m-nitroacetophenone 
• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 90945-65-6 2-acetoxy-1-(3-nitrophenyl)ethanone 

Downstream Products

• 121-92-6 3-nitrobenzoic acid 
• 124-38-9 carbon dioxide 
• 287944-26-7 (S)-(+)-1-(3-nitrophenyl)-1,2-ethanediol 
• 76116-24-0 (R)-1-(3-nitrophenyl)ethanol 
• 899596-52-2 4-chlorobenzyl 3-nitrobenzoate 
• 108521-49-9 prop-2-yn-1-yl 3-nitrobenzoate 
• 15875-88-4 2-chloroethyl 3-nitrobenzoate 
• 27800-03-9 m-Nitrobenzoesaeure-β-bromethylester 
• 6268-25-3 n-butyl 3-nitrobenzoate 
• 1415049-18-1 1-(3-nitrophenyl)-2-(piperidin-1-yl)ethane-1,2-dione 

Relevant articles and documents

Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer

Epidermal growth factor receptor (EGFR)-targeted therapy in non-small cell lung cancer represents a breakthrough in the field of precision medicine. Previously, we have identified a lead compound, furanopyrimidine 2, which contains a (S)-2-phenylglycinol

Regioselective three-component synthesis of 1,2-diarylindoles from cyclohexanones, α-hydroxyketones and anilines under transition-metal-free conditions

A facile method for the one-pot synthesis of 1,2-diarylindoles under transition-metal-free conditions is described. Cyclohexanones were used as the aryl sources via the dehydrogenative aromatization process. One C-C and two C-N bonds were selectively formed via a domino reaction. This protocol provides a convenient approach for the construction of valuable bioactive 1,2-diarylindoles from readily available cyclohexanones, α-hydroxyketones and anilines.

Microbial transformation of 2-hydroxy and 2-acetoxy ketones with Geotrichum sp.

Biotransformation of a series of o-, m- and p-substituted α-hydroxy- and α-acetoxyphenylethanones 1a-h and 9a-g with Geotrichum sp. led to the corresponding 1,2-diols 2 and/or monoacetates 10 in moderate to excellent enantiomeric excesses. α-Hydroxy- and α-acetoxyphenylethanones and their m- and p-derivatives gave preponderantly the S-configuration products while in the case of the o-derivatives R-alcohol was provided as the major enantiomer. The results of stereoselectivity were discussed. (C) 2000 Elsevier Science Ltd.

Antisecretory guanidine derivatives and pharmaceutical compositions containing them

The guanidine derivative has the formula: STR1 where X is O or S: Y is N, CH or CCH3 : m is 0 or 1: R1 is hydrogen and R2 cyano, trifluoroacetyl, C1-6 alkanoyl, 4,5-dihydro-4-oxothiazol-2-yl or A-B where A is 3,4-dioxocyclobutene-1,2-diyl or C=Z where Z is oxygen, sulphur, NCN, NNO2, CHNO2, NCONH2, C(CN)2, NCOR6, NCO2 R6, NSO2 R6 or NR7 where R6 is C1-6 alkyl and R7 is hydrogen or C1-6 alkyl and B is C1-6 alkyl, alkoxy or alkylthio or NR8 R9 where R8 and R9 are hydrogen, C1-10 alkyl, C3-10 -alkenyl, alkynyl or alkoxyalkyl, C2-6 (primary hydroxy)alkyl, or, when R9 is hydrogen, R8 is 2-[[5-dimethylaminomethylfuran-2-yl]methylthio]-ethylamino or R8 and R9 are together a 5- or 6-membered non-aromatic ring optionally containing an additional N or O; or R1 and R2 are together imidazolidin-2-ylidene: R3 is hydrogen or fluorine: R4 is halogen or methyl: R5 is hydrogen, C1-6 alkyl or C3-10 alkoxyalkyl: and the salts thereof.