108526-92-7Relevant academic research and scientific papers
Two Epimeric Dibromo Nitriles from the Australian Sponge Aplysina laevis
Capon, Robert J.,MacLeod, John K.
, p. 341 - 346 (2007/10/02)
Two dibromo nitriles, (1' R,5' S,6' S)-2-(3',5'-dibromo-1',6'-dihydroxy-4'-oxocyclohex-2'-enyl)acetonitrile (5) and the (1' R,5' R,6' S) epimer (6), possessing antimicrobial activity, have been isolated from the sponge Aplysina laevis (Carter).Cometabolites (+)-aeroplysinin-1 (1) and the dibromo ketone (2) were also identified.Structures (5) and (6) were assigned on the basis of spectroscopic evidence and synthesis from (1).
