1085337-59-2

Basic information

• Product Name: 4-bromo-1-tosyl-3-[2-(trimethylsilylethynyl)-1,3-dithian-2-yl]methyl-1H-indole
• Synonyms: 4-bromo-1-tosyl-3-[2-(trimethylsilylethynyl)-1,3-dithian-2-yl]methyl-1H-indole
• CAS NO: 1085337-59-2
• Molecular Weight: 578.69
• Mol File: 1085337-59-2.mol

Chemical Properties

• CAS DataBase Reference: 4-bromo-1-tosyl-3-[2-(trimethylsilylethynyl)-1,3-dithian-2-yl]methyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-1-tosyl-3-[2-(trimethylsilylethynyl)-1,3-dithian-2-yl]methyl-1H-indole(1085337-59-2)
• EPA Substance Registry System: 4-bromo-1-tosyl-3-[2-(trimethylsilylethynyl)-1,3-dithian-2-yl]methyl-1H-indole(1085337-59-2)

Safety Data

• Hazardous Substances Data: 1085337-59-2(Hazardous Substances Data)

Upstream product

• 1085337-58-1 4-bromo-3-(bromomethyl)-1-tosyl-1H-indole 
• 76649-03-1 2-<(trimethylsilyl)ethynyl>-1,3-dithiane 

Relevant articles and documents

Total synthesis of (±)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group

(Chemical Equation Presented) Ergot alkaloids and their synthetic analogs have been reported to exhibit broad biological activity. We investigated direct construction of the C/D ring system of ergot alkaloids based on palladium-catalyzed domino cyclization of amino allenes. With this biscyclization as the key step, total synthesis of (±)-lysergic acid, (±)-lysergol, and (±)-isolysergol was achieved.