108535-80-4

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 629-41-4 1,8-Octanediol 
• 98-59-9 p-toluenesulfonyl chloride 
• 103010-10-2 8-(p-methylbenzenesulfonyloxy)-1-octanol 
• 51326-52-4 8-(tetrahydro-2H-pyran-2-yloxy)octan-1-ol 

Downstream Products

• 19754-58-6 2-dec-9-ynyloxy-tetrahydro-pyran 
• 1243266-50-3 2-(8-(3,4,5-tris(2-(2-(2-ethoxyethoxy)ethoxy)ethoxy)benzyloxy)octyloxy)tetrahydro-2H-pyran 
• 103010-10-2 8-(p-methylbenzenesulfonyloxy)-1-octanol 

Relevant academic research and scientific papers

Biosynthesic Studies of Marine Lipids. 11. Synthesis, Biosynthesis, and Absolute Configuration of the Internally Branched Demospongic Acid, 22-Methyl-5,9-octacosadienoic Acid

The 14C-labeled short-chain fatty acid 10-methylhexadecanoic acid (10-Me-16:0) as well as its hitherto undescribed 10R and 10S antipodes was incorporated into the marine sponge Aplysina fistularis and transformed in situ into 22-methyl-5,9-octacosadienoic acid (22-Me-Δ5,9-28:2) by chain elongation.No qualitative specificity between the two enantiomers was observed. Methionine was also incorporated into the sponge to investigate the methylation process; a rapid incorporation into the short branched fatty acids occurred with subsequent chain elongation.Both enantiomers were synthesized starting from (+)-pulegone to determine the absolute configuration of the 22-methyl-5,9-octacosadienoic (22-Me-Δ5,9-28:2) acid.The naturally occurring acid has the 22R configuration.

THERAPY FOR DRY EYE (DE) AND MEIBOMIAN GLAND DYSFUNCTION (MGD) BASED ON THE REPLACEMENT OF O-ACYL-Ω-HYDROXY FATTY ACIDS (OAHFA)

The present invention relates to a process for preparing a fatty acid, a fatty acid obtainable by said process, a composition comprising said fatty acid, an eye drop comprising said fatty acid and a method for treating dry eye disease or Meibomian gland d

EPR spectroscopic characterization of local nanoscopic heterogeneities during the thermal collapse of thermoresponsive dendronized polymers

(Figure Presented) The collapse transition of thermoresponsive dendronized polymers was characterized on a molecular scale by CW EPR spectroscopy. Aggregation of the polymer is triggered by dynamic structural inhomogeneities of a few nanometers, and the dehydration of the polymer chains proceeds, despite the sharp phase transition, over a temperature interval of at least 30°C (see picture).

Ti(III) chloride: A novel reagent for the chemoselective deprotection of tetrahydropyranyl ethers

Ti(III) chloride was found to be an effective catalyst for the deprotection of tetrahydropyranyl ethers of alcohols and phenols at an ambient temperature. Allyl ether, benzyl ether, tert-butyl-diphenylsilyl (TBDPS) ether, p-toluenesulfonate ester and isomerizable double bond were found to be compatible under the reaction conditions.

A facile route to the deprotection of sulfonate esters and sulfonamides with low valent titanium reagents

A novel method for the cleavage of N/O-tosyl bonds by low-valent titanium is reported. TBDPS ether, THP ether, and olefin are found to be compatible under the reaction conditions.