103010-10-2

Basic information

• Product Name: 1,8-Octanediol, mono(4-methylbenzenesulfonate)
• Synonyms: 8-hydroxy-1-tosyloxyoctane;Toluene-4-sulfonic acid 8-hydroxy-octyl ester;1,8-octanediol monotosylate;8-hydroxyoctyl 4-methylbenzenesulfonate;8-(4-Methylphenylsulfonyloxy)-1-octanol
• CAS NO: 103010-10-2
• Molecular Formula: C15H24O4S
• Molecular Weight: 300.419
• Mol File: 103010-10-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,8-Octanediol, mono(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Octanediol, mono(4-methylbenzenesulfonate)(103010-10-2)
• EPA Substance Registry System: 1,8-Octanediol, mono(4-methylbenzenesulfonate)(103010-10-2)

Safety Data

• Hazardous Substances Data: 103010-10-2(Hazardous Substances Data)

Upstream product

• 50816-19-8 8-bromooctanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 629-41-4 1,8-Octanediol 
• 3185-99-7 Methyl p-tolyl sulfone 
• 153164-82-0 1-(allyloxy)-8-(prop-2-yn-1-yloxy)octane 
• 153164-83-1 8-allyloxyoctan-1-ol 
• 108535-80-4 1-(4-Methylphenylsulfonyloxy)-8-(2-tetrahydropyranyloxy)octane 

Downstream Products

• 108535-80-4 1-(4-Methylphenylsulfonyloxy)-8-(2-tetrahydropyranyloxy)octane 
• 94124-45-5 8-((1,1-Dimethylethyl)diphenylsilyloxy)octan-1-ol 
• 19008-71-0 8-aminooctan-1-ol 
• 312609-92-0 1-((1,1-Dimethylethyl)diphenylsilyloxy)-8-(4-methylphenylsulfonyloxy)octane 
• 105264-63-9 2-(8-hydroxyoctyl)isoindoline-1,3-dione 

Relevant articles and documents

Mycosamine orientation of amphotericin B controlling interaction with ergosterol: Sterol-dependent activity of conformation-restricted derivatives with an amino-carbonyl bridge

Amphotericin B (AmB 1) is known to assemble together and form an ion channel across biomembranes. The antibiotic consists of mycosamine and macrolactone moieties, whose relative geometry is speculated to be determinant for the drug's channel activity and

An Intramolecular Iodine-Catalyzed C(sp3)?H Oxidation as a Versatile Tool for the Synthesis of Tetrahydrofurans

The formation of ubiquitous occurring tetrahydrofuran patterns has been extensively investigated in the 1960s as it was one of the first examples of a non-directed remote C?H activation. These approaches suffer from the use of toxic transition metals in overstoichiometric amounts. An attractive metal-free solution for transforming carbon-hydrogen bonds into carbon-oxygen bonds lies in applying economically and ecologically favorable iodine reagents. The presented method involves an intertwined catalytic cycle of a radical chain reaction and an iodine(I/III) redox couple by selectively activating a remote C(sp3)?H bond under visible-light irradiation. The reaction proceeds under mild reaction conditions, is operationally simple and tolerates many functional groups giving fast and easy access to different substituted tetrahydrofurans.

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.