108536-14-7 Usage
General Description
1,2-Dioxetane, 3,4,4-trimethyl-3-[[(trimethylsilyl)oxy]methyl]- is a chemical compound that is a derivative of dioxetane, a three-membered heterocyclic compound. It is specifically modified with trimethylsilyl and hydroxy methyl groups. 1,2-Dioxetane, 3,4,4-trimethyl-3-[[(trimethylsilyl)oxy]methyl]- is commonly used in chemiluminescent assays, where it can be triggered to emit light by a chemical reaction. It has also shown potential applications in medical diagnostics and biotechnology due to its light-emitting properties. Additionally, it is a frequently used reagent in organic synthesis due to its ability to undergo efficient fragmentation reactions. However, it is important to handle this compound with caution, as it can be hazardous in certain forms and concentrations.
Check Digit Verification of cas no
The CAS Registry Mumber 108536-14-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,5,3 and 6 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 108536-14:
(8*1)+(7*0)+(6*8)+(5*5)+(4*3)+(3*6)+(2*1)+(1*4)=117
117 % 10 = 7
So 108536-14-7 is a valid CAS Registry Number.
108536-14-7Relevant articles and documents
Functionalized 1,2-Dioxetanes as Potential Phototherapeutic Agents: The Synthesis of Carboxylate, Carbonate, Carbamate, and Ether Derivatives of 3-(Hydroxymethyl)-3,4,4-trimethyl-1,2-dioxetane
Adam, Waldemar,Bhushan, Vydia,Fuchs, Rainer,Kirchgaessner, Uwe
, p. 3059 - 3062 (2007/10/02)
With gentle and efficient synthetic methods, 3-(hydroxymethyl)-3,4,4-trimethyl-1,2-dioxetane (1) can be transformed with appropriate electrophiles in moderate to good yields into functionalized derivatives of dioxetane 1.As electrophiles served carboxylic acids, chlorocarbonates, isocyanates, trialkyloxonium salts, and trialkylsilyl chlorides.With 1 these afford respectively dioxetanes with carboxylate, carbonate, carbamate, ether, and silyl ether functionalities.Nucleophilic activation of the hydroxymethyl substituent in the dioxetane 1 can be achieved under mild conditions by pyridine, 4-(dimethylamino)pyridine, potassium hydride, or butyllithium.Such functionalized dioxetanes serve as chemical sources of triplet excited carbonyl compounds which should find interesting utilization in photobiology and photomedicine, e.g. as potential phototherapeutic agents
