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methyl 1-(4-hydroxy-3-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1085709-12-1

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1085709-12-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1085709-12-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,5,7,0 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1085709-12:
(9*1)+(8*0)+(7*8)+(6*5)+(5*7)+(4*0)+(3*9)+(2*1)+(1*2)=161
161 % 10 = 1
So 1085709-12-1 is a valid CAS Registry Number.

1085709-12-1Downstream Products

1085709-12-1Relevant articles and documents

Synthesis and biological evaluation of a novel class of β-carboline derivatives

Chen, Hao,Gao, Pengchao,Zhang, Meng,Liao, Wei,Zhang, Jianwei

, p. 4155 - 4166 (2014)

In this study, several novel β-carboline derivatives, 1-(4-hydroxy-3-methoxyphenyl)-β-carboline-3-carboxyl-Trp-Trp-AA-OBzl compounds, were designed and synthesized as potential anticancer agents. Their in vitro cytotoxic activities were evaluated using me

Discovery of novel phosphatidylcholine-specific phospholipase C drug-like inhibitors as potential anticancer agents

Barker, David,Brar, Harpreet Kaur,Eurtivong, Chatchakorn,Leung, Euphemia,Leung, Ivanhoe K. H.,Paulin, Emily K.,Pilkington, Lisa I.,Rees, Shaun,Reynisson, Jóhannes,Sharma, Nabangshu,White, Reuben M.,Xu, Chris Sun,van Rensburg, Michelle

supporting information, (2019/12/24)

Phosphatidylcholine–specific phospholipase C (PC-PLC) is a promising target for new anticancer treatment. Herein, we report our work in the discovery of novel drug-like PC-PLC inhibitors. Virtual screening led to the identification of promising hits from

COMPOUNDS FOR TREATMENT OF METABOLIC SYNDROME

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Page/Page column 45; 46, (2012/10/18)

Present invention refers to new compounds of formula I or II, its synthesis and its use in the treatment of metabolic syndrome, particularly for the treatment of type I or type II diabetes and/or metabolic syndrome or metabolic disease or metabolic disorders.

Synthesis and antitumoral activity of novel 3-(2-substituted-1,3,4-oxadiazol-5-yl) and 3-(5-substituted-1,2,4-triazol-3-yl) β-carboline derivatives

Formagio, Anelise S. Nazari,Tonin, Lilian T. Duesman,Foglio, Mary Ann,Madjarof, Christiana,de Carvalho, Joao Ernesto,da Costa, Willian Ferreira,Cardoso, Flavia P.,Sarragiotto, Maria Helena

scheme or table, p. 9660 - 9667 (2009/04/06)

Several novel 1-substituted-phenyl β-carbolines bearing the 2-substituted-1,3,4-oxadiazol-5-yl and 5-substituted-1,2,4-triazol-3-yl groups at C-3 were synthesized and evaluated for their in vitro anticancer activity. The assay results pointed thirteen compounds with growth inhibition effect (GI50 50 values lying in the nanomolar concentration range (GI50 = 10 nM for both compounds). The 1-(N,N-dimethylaminophenyl)-3-(5-thioxo-1,2,4-triazol-3-yl) β-carboline (8g) was the most active compound, showing particular effectiveness on lung (GI50 = 0.06 μM), ovarian and renal cell lines. The potent anticancer activity presented for synthesized compounds 7a, 7h, and 8g, together with their easiness of synthesis, makes these compounds promising anticancer agents.

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