108574-11-4Relevant academic research and scientific papers
Ionic liquids as a reusable media for copper catalysis. Green access to alkenes using catalytic olefination reaction
Muzalevskiy, Vasily M.,Shastin, Aleksey V.,Shikhaliev, Namiq G.,Magerramov, Abel M.,Teymurova, Aytekin N.,Nenajdenko, Valentine G.
, p. 7159 - 7163 (2016/10/24)
It was demonstrated that ionic liquids are superb recyclable media for copper catalyzed reactions using catalytic olefination reaction as an example. As a result a novel green access to the halogenoalkenes was elaborated. Possibility to perform up to five reaction cycles without catalyst leaching and decreasing of the yield was demonstrated. A number of various ionic liquids was screened and 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim] [BF4]) was found the solvent with highest efficiency. Mild conditions, high atom economy comparing to other known methods, low amounts of wastes and possibility to recover ionic liquid are the advantages of the proposed method.
Efficient one-pot synthesis of 2-chloro-1,1, 1-trifluoro-2-alkenes under solvent-free conditions
Chen, Mu-Wang,Zhang, Xing-Guo,Zhong, Ping,Hu, Mao-Lin
experimental part, p. 756 - 763 (2009/09/05)
The improved one-pot Wittig reaction had been used to prepare trifluoromethyl-containing olefins under solvent-free conditions. Treatment of aldehydes with PPh3 and CF3CCl3 in the presence of K2CO3 at 100°C afforded 2-chloro-1,1,1-trifluoro-2-alkenes in g
A novel approach to fluoro-containing alkenes
Korotchenko, Vasily N,Shastin, Alexey V,Nenajdenko, Valentine G,Balenkova, Elisabeth S
, p. 7519 - 7527 (2007/10/03)
A new and general one-pot transformation of aromatic aldehydes to fluorinated olefins containing -CH=C(Cl)CF3 or -CH=C(F)CClF2 moieties is described. Freons CCl3CF3 and CCl2FCClF2 were used as trifluoromethyl and difluoromethyl C2-building blocks respectively. A proposed mechanism for the reaction is discussed.
Synthesis of trifluoromethylalkenes and alkynes. Trifluoromethyl captodative olefins
Laurent,Le Drean,Selmi
, p. 3071 - 3074 (2007/10/02)
β-ethylthio-β-trifluoromethylketones 3 and aldehydes 4 are easily prepared from β-chloroolefines 5 and 6. Trifluoromethylalkynes 7 and captodative alkenes 8 are obtained by reaction of KOH on aldehydes 6 or 4.
Efficient Carbonyl Addition of Polyfluorochloroethyl, -ethylidene, and -ethenyl Units by Means of 1,1,1-Trichloro-2,2,2-trifluoroethane and Zinc
Fujita, Makoto,Hiyama, Tamejiro
, p. 4377 - 4384 (2007/10/02)
Thermally stable zinc carbenoid CF3CCl2ZnCl was prepared from 1,1,1-trichloro-2,2,2-trifluoroethane and zinc powder in N,N-dimethylformamide and was allowed to add to carbonyls of aldehydes and α-keto esters in excellent yields to give 1-substituted 2,2-d
PRACTICAL WAYS FROM ALDEHYDES TO 2-CHLORO-1,1,1-TRIFLUORO-2-ALKENES AND 2-CHLORO-1,1-DIFLUORO-1-ALKEN-3-OLS
Fujita, Makoto,Hiyama, Tamejiro
, p. 3655 - 3658 (2007/10/02)
A reagent system CF3CCl3/Zn(>2 mol)/Ac2O transformed aldehydes to 2-chloro-1,1,1-trifluoro-2-alkenes exclusively, whereas CF3CCl3/Zn(>2 mol)/AlCl3(cat.) converted aldehydes into 2-chloro-1,1-difluoro-1-alken-3-ols.
