108575-36-6Relevant academic research and scientific papers
Imine/amide-imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-α inhibition
Negi, Arvind,Alex, Jimi Marin,Amrutkar, Suyog M.,Baviskar, Ashish T.,Joshi, Gaurav,Singh, Sandeep,Banerjee, Uttam C.,Kumar, Raj
, p. 5654 - 5661 (2015)
Microwave-accelerated synthesis and anticancer activity of novel imine/amide-imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole against a panel of seven cancer cell lines are reported for the first time. Compounds ARK-4, 10
Synthesis of 5-amino-4-cyanoformimidoylimidazoles and 5-amino-4- cyanoimidazoles from amidines
Yahyazadeh, Asieh,Sharifi, Zahra
, p. 1339 - 1343 (2006)
Imidazole and formimidoylimidazole derivatives have been synthesized in high yields by a reaction between amidine and a strong or weak base depending on reaction conditions and mainly on the nature of the base used to induced cyclization. All compounds ha
Synthesis of 5-amino-1-aryl-4-cyanoimidazoles from N-aryl-N′-(1,2-dicyanovinyl)-formamidines
Yahya-Zadeh,Booth
, p. 3225 - 3230 (2007/10/03)
The aryl-(Z)-N-[2-amino-1,2-dicyanovinyl]formamidine cyclize in the presence of base to give a 1,5-diamino-4-cyanoimidazole or a 1,5-diamino-4-(cyanoformimidoyl)imidazole, depending on the reaction conditions and the nature of the base used to induced cyc
