108579-40-4

Basic information

• Product Name: (E)-2-ethyl-1-trimethylsiloxy-3-phenyl-1-butene
• Synonyms: (E)-2-ethyl-1-trimethylsiloxy-3-phenyl-1-butene
• CAS NO: 108579-40-4
• Molecular Weight: 248.44
• Mol File: 108579-40-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-2-ethyl-1-trimethylsiloxy-3-phenyl-1-butene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-ethyl-1-trimethylsiloxy-3-phenyl-1-butene(108579-40-4)
• EPA Substance Registry System: (E)-2-ethyl-1-trimethylsiloxy-3-phenyl-1-butene(108579-40-4)

Safety Data

• Hazardous Substances Data: 108579-40-4(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 63883-69-2 (E)-2-ethyl-2-butenal 
• 7237-89-0 lithium diphenylcuprate 
• 100-58-3 phenylmagnesium bromide 

Relevant articles and documents

CHLOROSILANE-ACCELERATED CONJUGATE ADDITION OF CATALYTIC AND STOICHIOMETRIC ORGANOCOPPER REAGENTS

Trialkylsilyl chlorides, particularly in combination with hexamethylphosphoramide or 4-dimethylaminopyridine, dramatically accelerates the conjugate addition of catalytic and stoichiometric organocopper reagents onto enones, enals, and enoates, in which very high degrees of stereo- and chemoselectivities were observed.

Me3SiCl/HMPA ACCELERATED CONJUGATE ADDITION OF CATALYTIC COPPER REAGENT. STEREOSELECTIVE SYNTHESIS OF ENOL SILYL ETHER OF ALDEHYDE

Copper-catalyzed conjugate addition of Grignard reagents in the presence of Me3SiCl and HMPA proceeds in much higher yield than the reaction of conventional organocopper reagents and shows very good regio-, stereo-, and chemoselectivities.