1085965-89-4Relevant articles and documents
Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase
Tomita, Kenji,Oishi, Shinya,Ohno, Hiroaki,Peiper, Stephen C.,Fujii, Nobutaka
supporting information; experimental part, p. 7645 - 7649 (2009/12/07)
Kisspeptin-GPR54 signaling is involved in the suppression of cancer metastasis and regulation of hormonal secretion. Recently, matrix metalloproteinase mediated deactivation of kisspeptins through hydrolysis of the Gly-Leu peptide bond has been reported.