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1086378-35-9

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1086378-35-9 Usage

General Description

Methyl benzo[d]oxazole-7-carboxylate is a chemical compound with the molecular formula C10H7NO3. It is a derivative of benzo[d]oxazole, containing a methyl group and a carboxylate group. This chemical is commonly used as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical industry for the preparation of drug molecules. Methyl benzo[d]oxazole-7-carboxylate has potential applications as a building block in the synthesis of bioactive compounds and can also be used as a research tool in chemical and pharmaceutical research. Its specific properties and applications make it an important chemical in the field of organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 1086378-35-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,6,3,7 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1086378-35:
(9*1)+(8*0)+(7*8)+(6*6)+(5*3)+(4*7)+(3*8)+(2*3)+(1*5)=179
179 % 10 = 9
So 1086378-35-9 is a valid CAS Registry Number.

1086378-35-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 1,3-benzoxazole-7-carboxylate

1.2 Other means of identification

Product number -
Other names methyl benzoxazole-7-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1086378-35-9 SDS

1086378-35-9Relevant articles and documents

Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists

Hansen, Martin,Jacobsen, Stine Engesgaard,Plunkett, Shane,Liebscher, Gudrun Eckhard,McCorvy, John D.,Br?uner-Osborne, Hans,Kristensen, Jesper Langgaard

, p. 3933 - 3937 (2015)

N-Benzyl substitution of phenethylamine 5-HT2A receptor agonists has dramatic effects on binding affinity, receptor selectivity and agonist activity. In this paper we examine how affinity for the 5-HT2A/2C receptors are influenced by N-benzyl substitution of 4-bromo-2,5-dimethoxyphenethylamine derivatives. Special attention is given to the 2′ and 3′-position of the N-benzyl as such compounds are known to be very potent. We found that substitutions in these positions are generally well tolerated. The 2′-position was further examined using a range of substituents to probe the hydrogen bonding requirements for optimal affinity and selectivity, and it was found that small changes in the ligands in this area had a profound effect on their affinities. Furthermore, two ligands that lack a 2′-benzyl substituent were also found to have high affinity contradicting previous held notions. Several high-affinity ligands were identified and assayed for functional activity at the 5-HT2A and 5-HT2C receptor, and they were generally found to be less efficacious agonists than previously reported N-benzyl phenethylamines.

COMPOUND HAVING ZNF143 INHIBITORY ACTIVITY AND USE THEREOF

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Paragraph 0090; 0138; 0139, (2016/10/27)

PROBLEM TO BE SOLVED: To provide a compound having a ZNF143 inhibitory activity as well as to provide a ZNF143 inhibitory agent and pharmaceutical composition containing the same. SOLUTION: Provided is a compound represented by formula (I) or a salt thereof as well as a ZNF143 inhibitory agent containing the same and a pharmaceutical composition having the same as an active ingredient. A-B-C-D (I)[A is H, a methyl group, a naphthyl group, a phenyl group or a nitrogen-containing heterocyclic ring; B is as shown below, and C is an amide bond or a heteroaromatic ring containing N and O; D is a substituted/unsubstituted phenyl group or a monocyclic heteroaromatic ring containing N or S; and C and D are both fused heterocyclic ring or the like optionally having a substituent group.]. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPOandINPIT

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