1086409-82-6

Basic information

• Product Name: N-Hydroxy-11-azaartemisinin
• Synonyms: N-Hydroxy-11-azaartemisinin;(3R,5aS,6R,8aS,9R,12R,12aR)-11-Hydroxydecahydro-3,6,9-triMethyl-;CIMKGYLLDNUUNG-MBQCHNMNSA-N
• CAS NO: 1086409-82-6
• Molecular Formula: C₁₅H₂₃NO₅
• Molecular Weight: 297.34682
• Product Categories: Chiral Reagents;Drug Analogues;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents, Drug Analogues, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1086409-82-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 165-167 °C
• Boiling Point: 414.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.32±0.1 g/cm3(Predicted)
• Storage Temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform, Methanol
• PKA: 8.95±0.70(Predicted)
• CAS DataBase Reference: N-Hydroxy-11-azaartemisinin(CAS DataBase Reference)
• NIST Chemistry Reference: N-Hydroxy-11-azaartemisinin(1086409-82-6)
• EPA Substance Registry System: N-Hydroxy-11-azaartemisinin(1086409-82-6)

Safety Data

• Hazardous Substances Data: 1086409-82-6(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Upstream product

• 63968-64-9 C₁₂H₁₃O₂(CH₃)3(O)(OO) 

Downstream Products

• 1086410-20-9 C₂₄H₃₃NO₅ 

Relevant articles and documents

New orally active amino- and hydroxy-functionalized 11-azaartemisinins and their derivatives with high order of antimalarial activity against multidrug-resistant Plasmodium yoelii in swiss mice1

By use of artemisinin 1 as the starting material, two new amino- and hydroxy-functionalized 11-azaartemisinins 9 and 11 and their derivatives 12a-g, 13a-g, 14a-g, and 15a-c have been prepared and screened for antimalarial activity by oral route against mu