108641-77-6

Basic information

• Product Name: 2-(1-methyl-1H-benzo[d]imidazol-2-yl)-1-phenylethan-1-ol
• CAS NO: 108641-77-6
• Molecular Weight: 252.316
• Mol File: 108641-77-6.mol

Chemical Properties

• CAS DataBase Reference: 2-(1-methyl-1H-benzo[d]imidazol-2-yl)-1-phenylethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-methyl-1H-benzo[d]imidazol-2-yl)-1-phenylethan-1-ol(108641-77-6)
• EPA Substance Registry System: 2-(1-methyl-1H-benzo[d]imidazol-2-yl)-1-phenylethan-1-ol(108641-77-6)

Safety Data

• Hazardous Substances Data: 108641-77-6(Hazardous Substances Data)

Upstream product

• 102549-93-9 1-methyl-2-phenethyl-1H-benzo[d]imidazole 
• 2876-08-6 1,2-dimethyl-1H-benzimidazole 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Iridium-Catalyzed Asymmetric Borylation of Unactivated Methylene C(sp3)-H Bonds

Herein, we show the highly enantioselective borylation of unactivated methylene C(sp3)-H bonds in 2-alkylpyridines and 2-alkyl-1,3-azole derivatives using an iridium-BINOL-based chiral monophosphite catalyst system. Quantum chemical calculations using the artificial force induced reaction (AFIR) method suggested that a monophosphite-Ir-tris(boryl) complex generates a narrow chiral reaction pocket where the differentiation of the enantiotopic methylene C-H bonds is accomplished through an assembly of multiple noncovalent interactions.

Iridium-Catalyzed Asymmetric Borylation of Unactivated Methylene C(sp3)-H Bonds

Herein, we show the highly enantioselective borylation of unactivated methylene C(sp3)-H bonds in 2-alkylpyridines and 2-alkyl-1,3-azole derivatives using an iridium-BINOL-based chiral monophosphite catalyst system. Quantum chemical calculations using the artificial force induced reaction (AFIR) method suggested that a monophosphite-Ir-tris(boryl) complex generates a narrow chiral reaction pocket where the differentiation of the enantiotopic methylene C-H bonds is accomplished through an assembly of multiple noncovalent interactions.

ORGANOLITHIUM AND ORGANOSODIUM COMPOUNDS OF N-SUBSTITUTED 2-ALKYLBENZIMIDAZOLES

Organolithium and organosodium compounds of 1,2-dimethyl-, 1-methyl-2-ethyl-,1-methyl-2-propyl-, and 1-phenyl-2-methylbenzimidazole, containing the metal in the alkyl group at position C(2), were obtaind by metallation.It was found that metallation can be complicated by the addition of metalling reagent at the C=N bond of the heterocycle.It was shown that the obtained organometallic compounds can be used for the synthesis of various derivatives of benzimidazole.