1086533-18-7

Basic information

• Product Name: Quinoline, 2,4-dichloro-3-fluoro-6-Methoxy-
• Synonyms: Quinoline, 2,4-dichloro-3-fluoro-6-Methoxy-;2,4-DICHLORO-3-FLUORO-6-METHOXYQUINOLINE
• CAS NO: 1086533-18-7
• Molecular Formula: C10H6Cl2FNO
• Molecular Weight: 246.0651432
• EINECS: -0
• Mol File: 1086533-18-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Quinoline, 2,4-dichloro-3-fluoro-6-Methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2,4-dichloro-3-fluoro-6-Methoxy-(1086533-18-7)
• EPA Substance Registry System: Quinoline, 2,4-dichloro-3-fluoro-6-Methoxy-(1086533-18-7)

Safety Data

• Hazardous Substances Data: 1086533-18-7(Hazardous Substances Data)

Upstream product

• 473-87-0 2-fluoromalonic acid 
• 90-04-0 2-methoxy-phenylamine 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 426842-85-5 4-chloro-3-fluoro-6-methoxyquinoline 
• 1080636-09-4 4-(2-(3-fluoro-6-methoxyquinolin-4-yl)-2-hydroxyethoxy)-1-(3-phenylcyclobutyl)piperidine-4-carboxylic acid 

Relevant articles and documents

A facile two-step synthesis of 3-fluoro-6-methoxyquinoline

A facile two-step synthesis of 3-fluoro-6-methoxyquinoline is described. p-Anisidine was heated at reflux with 2-fluoromalonic acid in the presence of phosphorus oxychloride to produce 2,4-dichloro-3-fluoro-6-methoxyquinoline. This was followed by hydrogenolysis to produce 3-fluoro-6-methoxyquinoline.

Hepatitis C virus inhibitors

Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

NOVEL SUBSTITUTED BICYCLIC AROMATIC COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS

The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.