108664-93-3Relevant academic research and scientific papers
Aqueous and Visible-Light-Promoted C-H (Hetero)arylation of Uracil Derivatives with Diazoniums
Liu, An-Di,Wang, Zhao-Li,Liu, Li,Cheng, Liang
, p. 16434 - 16447 (2021/11/16)
Direct C5 (hetero)arylation of uracil and uridine substrates with (hetero)aryl diazonium salts under photoredox catalysis with blue light was reported. The coupling proceeds efficiently with diazonium salts and heterocycles in good functional group tolerance at room temperature in aqueous solution without transition-metal components. A plausible radical mechanism has been proposed.
New water soluble Pd-imidate complexes as highly efficient catalysts for the synthesis of C5-arylated pyrimidine nucleosides
Kapdi, Anant,Gayakhe, Vijay,Sanghvi, Yogesh S.,Garcia, Joaquin,Lozano, Pedro,Da Silva, Ivan,Perez, Jose,Serrano, J. Luis
, p. 17567 - 17572 (2014/05/06)
The direct reactions between the precursors trans-[Pd(imidate) 2(SMe2)2] and 1,3,5-triaza-7-phosphaadamantane (PTA) yield new water-soluble palladium(ii) complexes trans-[Pd(imidate) 2(PTA)2](imidate
Linear Free Energy Relationship Studies of 5-Substituted 2,4-Dioxopyrimidine Nucleosides
Chang, George,Mertes, Mathias P.
, p. 3625 - 3631 (2007/10/02)
The development of a direct and efficient palladium(0)-catalyzed biaryl coupling reaction permitted the synthesis of a series of N1-substituted 5-aryl-2,4-dioxopyrimidines.The physical and spectral properties of these compounds were determined and correlated by various linear free energy relationships.The relationships between the physical and spectral data with Hammett ? constants proved useful in analyzing the electron distribution of the heterocycle.Although a significant degree of orbital overlap and interaction between the substituents and the pyrimidine ring was observed, it is doubtful that the interactions are comparable to those of a benzene ring system.
