Welcome to LookChem.com Sign In|Join Free
  • or

54-42-2

Post Buying Request

54-42-2 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
5-Iodo-2’-Deoxyuridine
Cas No: 54-42-2
No Data 1 Kilogram 100 Kilogram/Month Beijing Chemdow Co., Ltd Contact Supplier
5-Iodo-2-Deoxyuridine 5-IDU CAS NO.54-42-2 Pharma intermediate worldwide TOP pharma factory vendor
Cas No: 54-42-2
USD $ 2000.0-2500.0 / Kilogram 1 Kilogram 100 Kilogram/Month Innobio Pharm Co.,Ltd Contact Supplier
(+)-5-Iodo-2'-deoxyuridine Manufacturer
Cas No: 54-42-2
USD $ 32.0-50.0 / Kilogram 1 Kilogram 30 Metric Ton/Month XINXIANG AURORA BIOTECHNOLOGY CO., LTD. Contact Supplier
High quality 5-Iodo-2'-Deoxyuridine supplier in China
Cas No: 54-42-2
No Data 1 Metric Ton 30 Metric Ton/Month Simagchem Corporation Contact Supplier
High quality 54-42-2 (+)-5-Iodo-2'-deoxyuridine
Cas No: 54-42-2
USD $ 1300.0-1600.0 / Kilogram 1 Kilogram 99999 Kilogram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
CAS: 54-42-2 2'-Deoxy-5-iodouridine
Cas No: 54-42-2
No Data 1 Kilogram 100 Kilogram/Day Kono Chem Co.,Ltd Contact Supplier
(+)-5-Iodo-2'-deoxyuridine
Cas No: 54-42-2
No Data 1 Kilogram 1 Metric Ton/Month Henan Allgreen Chemical Co.,Ltd Contact Supplier
Factory high quality idoxuridine
Cas No: 54-42-2
No Data 1 Kilogram 10000 Kilogram/Month Shanghai Bokchang Chemical Science and Technology Co.,Ltd Contact Supplier
Idoxuridine
Cas No: 54-42-2
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
(+)-5-Iodo-2'-deoxyuridine Manufacturer/High quality/Best price/In stock
Cas No: 54-42-2
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier

54-42-2 Usage

Definition

ChEBI: A pyrimidine 2'-deoxyribonucleoside compound having 5-iodouracil as the nucleobase; used as an antiviral agent.

Uses

Antiviral;Nucleic acid synthesis inhibitors

Chemical Properties

Crystalline Solid

Uses

Used as an antiviral

Uses

Antitumor nucleoside enantiomer thymidine kinase used as potential antiviral agents.

Brand name

Dendrid (Alcon); Herplex (Allergan); Stoxil (GlaxoSmithKline).

Uses

A cytotoxic analog of thymidine, antiviral

54-42-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1336001)  Idoxuridine  United States Pharmacopeia (USP) Reference Standard 54-42-2 1336001-250MG 4,662.45CNY Detail
Alfa Aesar (A11542)  (+)-5-Iodo-2'-deoxyuridine, 98%    54-42-2 5g 2453.0CNY Detail
Alfa Aesar (A11542)  (+)-5-Iodo-2'-deoxyuridine, 98%    54-42-2 1g 607.0CNY Detail
TCI America (I0258)  5-Iodo-2'-deoxyuridine  >99.0%(T) 54-42-2 25g 6,450.00CNY Detail
TCI America (I0258)  5-Iodo-2'-deoxyuridine  >99.0%(T) 54-42-2 5g 1,850.00CNY Detail
TCI America (I0258)  5-Iodo-2'-deoxyuridine  >99.0%(T) 54-42-2 1g 550.00CNY Detail

54-42-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-iodo-2'-deoxyuridine

1.2 Other means of identification

Product number -
Other names Idoxuridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54-42-2 SDS

54-42-2Synthetic route

2'-deoxyuridine
951-78-0

2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With iodine; silver nitrate In methanol at 40℃; for 3h;100%
With iodine; silver nitrate In methanol at 40℃; for 3h;100%
With sodium azide; Iodine monochloride In acetonitrile at 25℃; for 24h; Product distribution; Mechanism; other uracil nucleosides; other halogenation agents; var. temp. and time;96%
3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With sodium methylate In methanol for 1h; Ambient temperature;90%
With methanol; sodium methylate at 20℃; for 1h;
5-trimethylstannyl-2'-deoxyuridine
146629-34-7

5-trimethylstannyl-2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide; acetic acid; sodium iodide In chloroform for 0.00416667h; Irradiation;
C23H17Cl2IN2O7

C23H17Cl2IN2O7

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With ammonia In methanol at 30℃; for 16h;
2'-deoxyuridine
951-78-0

2'-deoxyuridine

5-iodouracil
696-07-1

5-iodouracil

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
at 37℃; for 6h; alginate gel-entrapped cells of auxotrophic thymine-dependent strain of E. coli, ammonium acetate buffer pH 5.8;
5-iodouracil
696-07-1

5-iodouracil

thymidine
50-89-5

thymidine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

thymin
65-71-4

thymin

Conditions
ConditionsYield
With thymidine phosphorylase from Escherichia coli In phosphate buffer at 35℃; for 2h; pH=7.0; Title compound not separated from byproducts;A 88 % Chromat.
B n/a
3',5'-di-O-acetyl-2'-deoxyuridine
13030-62-1

3',5'-di-O-acetyl-2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 93 percent / LiI, ceric ammonium nitrate (CAN) / acetonitrile / 1 h / 80 °C / other conditions and reagents investigated
2: 90 percent / 0.1 M NaOMe / methanol / 1 h / Ambient temperature
View Scheme
C5-chloromercuri-2'-deoxyuridine
65505-76-2

C5-chloromercuri-2'-deoxyuridine

1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril
51592-06-4

1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With sodium iodide In water
2'-deoxyuridine
951-78-0

2'-deoxyuridine

5-iodouracil
696-07-1

5-iodouracil

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

uracil
66-22-8

uracil

Conditions
ConditionsYield
With thymidine phosphorylase from Escherichia coli (E.C. 2.4.2.4) immobilized on Sepabeads EC-EP In aq. phosphate buffer at 20℃; for 3h; pH=7.5; Reagent/catalyst; Enzymatic reaction;
3',5'-di-O-acetyl-2'-deoxyuridine
13030-62-1

3',5'-di-O-acetyl-2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ammonium cerium (IV) nitrate; iodine / acetonitrile / 1 h / 80 °C
2: tetraphosphorus decasulfide / 1,4-dioxane / Reflux
3: sodium hydride / methanol / 0.17 h / 0 - 20 °C
4: aq. phosphate buffer; tert-butyl alcohol / Radiolysis
View Scheme
3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetraphosphorus decasulfide / 1,4-dioxane / Reflux
2: sodium hydride / methanol / 0.17 h / 0 - 20 °C
3: aq. phosphate buffer; tert-butyl alcohol / Radiolysis
View Scheme
5-iodo-4-thio-2'-deoxyuridine
1313407-40-7

5-iodo-4-thio-2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
In aq. phosphate buffer; tert-butyl alcohol Radiolysis;
2'-deoxyuridine
951-78-0

2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: pyridine / 24 h / 20 °C
2: ammonium cerium (IV) nitrate; iodine / acetonitrile / 1 h / 80 °C
3: tetraphosphorus decasulfide / 1,4-dioxane / Reflux
4: sodium hydride / methanol / 0.17 h / 0 - 20 °C
5: aq. phosphate buffer; tert-butyl alcohol / Radiolysis
View Scheme
5-iodouracil
696-07-1

5-iodouracil

thymidine
50-89-5

thymidine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With recobinant purine nucleoside phosphorylase from Escherichia coli In aq. phosphate buffer pH=6.8; Heating; Enzymatic reaction;
C5H9O7P(2-)*2K(1+)

C5H9O7P(2-)*2K(1+)

5-iodouracil
696-07-1

5-iodouracil

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With E-pyrimidine nucleoside phosphorylase-0002 In aq. buffer at 50℃; for 2h; pH=9; Equilibrium constant; Enzymatic reaction;
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate
86163-17-9

methyl (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

Conditions
ConditionsYield
With palladium diacetate; triethylamine; triphenylphosphine In 1,4-dioxane for 14h; Heating;100%
Stage #1: 5-Iodo-2'-deoxyuridine With C26H32N8O6P2PdS2 In acetonitrile at 80℃; for 0.0833333h; Heck Reaction; Inert atmosphere;
Stage #2: acrylic acid methyl ester With triethylamine In acetonitrile at 80℃; for 8h; Heck Reaction; Inert atmosphere;
92%
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 100℃; for 1h;87%
9-ethynyl-closo-1,7-dodecaborane
80755-88-0

9-ethynyl-closo-1,7-dodecaborane

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-[(1,7-dicarba-closo-dodecaboran-9-yl)ethyn-1-yl]-2′-deoxyuridine

5-[(1,7-dicarba-closo-dodecaboran-9-yl)ethyn-1-yl]-2′-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 80℃; Sonogashira Cross-Coupling; Inert atmosphere;100%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine
148134-86-5

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine

Conditions
ConditionsYield
With 1H-imidazole In pyridine for 33h;99%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 3h;99.8%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 60h;99%
4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine
104375-88-4

2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine

Conditions
ConditionsYield
With pyridine Ambient temperature;99%
With pyridine; triethylamine at 20℃; for 1h;98%
With pyridine In triethylamine at 20℃; for 5h;96%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

acetic anhydride
108-24-7

acetic anhydride

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

Conditions
ConditionsYield
With pyridine at 20℃; for 16.5h;99%
With pyridine at 20℃;98%
With pyridine at 25℃; for 20h;97%
3,3-bis-(trifluoromethyl)-4,4,4-trifluoro-1-butyne
14115-48-1

3,3-bis-(trifluoromethyl)-4,4,4-trifluoro-1-butyne

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(4,4,4-trifluoro-3,3-bis(trifluoromethyl)but-1-ynyl)-2'-deoxyuridine
1032735-58-2

5-(4,4,4-trifluoro-3,3-bis(trifluoromethyl)but-1-ynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 22℃; for 96h; Sonogashira coupling; Inert atmosphere;98%
acrylic acid n-butyl ester
141-32-2

acrylic acid n-butyl ester

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

(E)-5-[2-(n-butyloxycarbonyl)vinyl]-2′-deoxyuridine

(E)-5-[2-(n-butyloxycarbonyl)vinyl]-2′-deoxyuridine

Conditions
ConditionsYield
With 3,3′,3″-phosphinetriyltribenzenesulfonate; palladium diacetate; triethylamine In water; acetonitrile at 80℃; for 1.5h; Solvent; Temperature; Reagent/catalyst; Inert atmosphere;98%
With tri(3-sulfonatophenyl)phosphine trisodium salt; palladium diacetate; triethylamine In water; acetonitrile at 80℃; Heck reaction; Inert atmosphere;74%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-methoxycarbonyl-2’-deoxyuridine

5-methoxycarbonyl-2’-deoxyuridine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 70℃;98%
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
69304-37-6

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-iodo-3',5'-O-[(tetraisopropyl)disiloxane-1,3-diyl]-2'-deoxyuridine
129507-76-2

5-iodo-3',5'-O-[(tetraisopropyl)disiloxane-1,3-diyl]-2'-deoxyuridine

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide for 12h;97%
With pyridine at 20℃;97%
With pyridine at 20℃;84%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 3h; silylation;
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

phenylboronic acid
98-80-6

phenylboronic acid

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-phenylpyrimidine-2,4(1H,3H)-dione
76756-28-0

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-phenylpyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With palladium diacetate; sodium carbonate; triphenylphosphine In water; acetonitrile at 70 - 80℃; for 4h; Suzuki-Miyaura Coupling; Inert atmosphere;97%
With palladium diacetate; sodium carbonate; triphenylphosphine In water; acetonitrile at 70 - 80℃; for 4h; Suzuki-Miyaura Coupling; Inert atmosphere;97%
With C30H24Cl2N2O10Pd2S2(2-)*2Na(1+); triethylamine In water at 60℃; for 3h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;93%
2-ethynylpyridine
1945-84-2

2-ethynylpyridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(2-pyridylethynyl)-2'-deoxyuridine
78824-48-3

5-(2-pyridylethynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; Inert atmosphere;97%
1-Heptene
592-76-7

1-Heptene

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(hept-1-en-1-yl)-2'-deoxyuridine
96962-44-6

5-(hept-1-en-1-yl)-2'-deoxyuridine

Conditions
ConditionsYield
With tributyl-amine; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 0.333333h; Heck reaction; Microwave irradiation;97%
With tributyl-amine; palladium diacetate In 1,4-dioxane; N,N-dimethyl-formamide at 100℃; for 0.333333h; Microwave irradiation;97%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

2-(tri-n-butylstannyl)benzofuran

2-(tri-n-butylstannyl)benzofuran

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1449768-52-8

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; Stille Cross Coupling;97%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

but-1-yn-4-yl thiobenzoate
211510-45-1

but-1-yn-4-yl thiobenzoate

5-(4-benzoylthio-1-butynyl)-2'-deoxyuridine
647852-33-3

5-(4-benzoylthio-1-butynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 22 - 24℃;96%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

acetyl chloride
75-36-5

acetyl chloride

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

Conditions
ConditionsYield
With acetic anhydride; acetic acid 1.) 0 deg C, 1 h, 2.) RT, 24 h;95%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

dimethyl sulfate
77-78-1

dimethyl sulfate

5-iodo-3-methyl-2′-deoxyuridine
35695-25-1

5-iodo-3-methyl-2′-deoxyuridine

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.166667h;95%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

3-methyl-N-(prop-2-yn-1-yl)butanamide
422284-33-1

3-methyl-N-(prop-2-yn-1-yl)butanamide

5-[3-(3-methylbutyrylamino)prop-1-ynyl]-2'-deoxyuridine

5-[3-(3-methylbutyrylamino)prop-1-ynyl]-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 20℃; for 4h;95%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

diphenylphosphane
829-85-6

diphenylphosphane

5-diphenylphosphine-2'-deoxyuridine
939057-19-9

5-diphenylphosphine-2'-deoxyuridine

Conditions
ConditionsYield
With triethylamine; palladium diacetate In N,N-dimethyl-formamide at 60℃; for 0.5h;95%
3-methoxyphenylboronic acid
10365-98-7

3-methoxyphenylboronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(3-methoxyphenyl)-2'-deoxyuridine
92510-79-7

5-(3-methoxyphenyl)-2'-deoxyuridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In water; N,N-dimethyl-formamide at 60℃; Suzuki cross-coupling; Inert atmosphere;95%
With [Pd(phthalimidate)2(1,3,5-triaza-7-phosphaadamantane)2]; triethylamine In water at 20 - 80℃; for 6h; Suzuki-Miyaura Coupling; Inert atmosphere;
4-tert-Butylphenylacetylene
772-38-3

4-tert-Butylphenylacetylene

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-((4-tert-butylphenyl)ethynyl)-2'-deoxyuridine
596107-17-4

5-((4-tert-butylphenyl)ethynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 40℃; for 25h; Sonogashira coupling;94%
With copper(l) iodide; tetra-(n-butyl)ammonium iodide; triphenylphosphine; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 20℃; for 24h; Sonogashira coupling;76%
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

2-(tributylstannyl)furan
118486-94-5

2-(tributylstannyl)furan

5-furan-2-yl-1-(β-D-2-deoxyribofuranos-1-yl)uracil
92233-50-6

5-furan-2-yl-1-(β-D-2-deoxyribofuranos-1-yl)uracil

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; for 2h; Stille coupling;94%
bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; for 2h; Stille coupling;94%
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane94%
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; Stille Cross Coupling;
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

1-Ethynyl-1-cyclohexanol
78-27-3

1-Ethynyl-1-cyclohexanol

5-((1-hydroxycyclohexyl)ethynyl)-2'-deoxyuridine
936332-87-5

5-((1-hydroxycyclohexyl)ethynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 50℃; for 7h; Sonogashira coupling;94%
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide
2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(2-methylphenyl)-2'-deoxyuridine
1373213-45-6

5-(2-methylphenyl)-2'-deoxyuridine

Conditions
ConditionsYield
With sodium tetrachloropalladate; trisodium tris(3-sulfophenyl)phosphine; potassium hydroxide In water at 100℃; for 24h; Suzuki-Miyaura coupling; Inert atmosphere;94%
With sodium tetrachloropalladate(II); potassium hydroxide In water at 100℃; for 1h; Suzuki-Miyaura Coupling; Inert atmosphere; Microwave irradiation;30%
With sodium tetrachloropalladate(II); potassium hydroxide In water at 100℃; for 24h; Concentration; Time; Suzuki-Miyaura Coupling; Inert atmosphere; Green chemistry;22%
benzofuran-2-boronic acid
98437-24-2

benzofuran-2-boronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1449768-52-8

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With [Pd(succinimidate)2(1,3,5-triaza-7-phosphaadamantane)2]; triethylamine In water at 80℃; for 0.0833333h; Catalytic behavior; Concentration; Suzuki-Miyaura Coupling; Microwave irradiation; Inert atmosphere;94%
With C30H24Cl2N2O10Pd2S2(2-)*2Na(1+); triethylamine In water at 60℃; for 3h; Solvent; Reagent/catalyst; Temperature; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;89%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

propionic acid anhydride
123-62-6

propionic acid anhydride

3′,5′-bis-O-propionyl-5-iodo-2′-deoxyuridine
4833-05-0

3′,5′-bis-O-propionyl-5-iodo-2′-deoxyuridine

Conditions
ConditionsYield
With pyridine at 60℃; for 8h; Inert atmosphere;93%
With pyridine85%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

tri-n-butyl(vinyl)tin
7486-35-3

tri-n-butyl(vinyl)tin

5-vinyl-2'-deoxyuridine
55520-67-7

5-vinyl-2'-deoxyuridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 12h; Inert atmosphere; Reflux;92%
With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran for 24h; Inert atmosphere; Reflux;50%
With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran for 24h; Heating;47%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

1-(2-deoxy-β-D-ribofuranosyl)-5-[2-(trimethylsilyl)ethynyl]uracil
151362-01-5

1-(2-deoxy-β-D-ribofuranosyl)-5-[2-(trimethylsilyl)ethynyl]uracil

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 55℃; for 24h; Sonogashira coupling;92%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile at 50℃; for 3.5h; Schlenk technique; Inert atmosphere;85%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile for 3.5h; Inert atmosphere; Heating;82%
4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(4'-fluorophenyl)-2'-deoxyuridine

5-(4'-fluorophenyl)-2'-deoxyuridine

Conditions
ConditionsYield
With palladium diacetate; sodium carbonate; tris-(m-sulfonatophenyl)phosphine In water; acetonitrile at 80℃; Suzuki coupling;92%
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In water; N,N-dimethyl-formamide at 60℃; Suzuki cross-coupling; Inert atmosphere;78%
With palladium diacetate; sodium carbonate; triphenylphosphine In water at 120℃; for 0.166667h; Suzuki-Miyaura Coupling; Inert atmosphere; Sealed tube; Microwave irradiation;74%
With [Pd(phthalimidate)2(1,3,5-triaza-7-phosphaadamantane)2]; triethylamine In water at 20 - 80℃; for 6h; Suzuki-Miyaura Coupling; Inert atmosphere;
methyl 3-ethynylbenzoate
10602-06-9

methyl 3-ethynylbenzoate

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

3-[3-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-2,3-dihydro-furo[2,3-d]pyrimidin-6-yl]-benzoic acid methyl ester

3-[3-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-2,3-dihydro-furo[2,3-d]pyrimidin-6-yl]-benzoic acid methyl ester

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 55℃; for 12h;92%

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields