108664-94-4Relevant academic research and scientific papers
New water soluble Pd-imidate complexes as highly efficient catalysts for the synthesis of C5-arylated pyrimidine nucleosides
Kapdi, Anant,Gayakhe, Vijay,Sanghvi, Yogesh S.,Garcia, Joaquin,Lozano, Pedro,Da Silva, Ivan,Perez, Jose,Serrano, J. Luis
, p. 17567 - 17572 (2014/05/06)
The direct reactions between the precursors trans-[Pd(imidate) 2(SMe2)2] and 1,3,5-triaza-7-phosphaadamantane (PTA) yield new water-soluble palladium(ii) complexes trans-[Pd(imidate) 2(PTA)2](imidate
Efficient synthesis of unprotected C-5-Aryl/Heteroaryl-2'-deoxyuridine via a suzuki-miyaura reaction in aqueous media
Fresneau, Nathalie,Hiebel, Marie-Aude,Agrofoglio, Luigi A.,Berteina-Raboin, Sabine
, p. 14409 - 14417 (2013/02/25)
Following our previous results on an environmentally benign one-pot Sonogashira-cyclization protocol to obtain substituted furopyrimidine nucleosides under aqueous conditions, we investigate herein the Suzuki-Miyaura cross-coupling reactions of aryl and h
Syntheses and fluorescence of RNA conjugates having pyrene-modified adenosine and nitrobenzene-modified uridine base pairs
Fukuda, Minoru,Nakamura, Mitsunobu,Takada, Tadao,Yamana, Kazushige
experimental part, p. 1732 - 1735 (2010/05/18)
We prepared RNA duplexes possessing 2′-O-(1-pyrenylmethyl)adenosine and 5-(4-nitrophenyl)uridine base pairs. In the duplexes, pyrene serves as a photo-excitable electron donor and 5-(4-nitrophenyl)uridine acts as an electron acceptor. The donor-acceptor-modified RNA duplexes showed very weak fluorescence originating from the pyrene monomer and excimer emissions, which occur due to electron transfer from the excited pyrene to the nitrobenzene acceptor.
Linear Free Energy Relationship Studies of 5-Substituted 2,4-Dioxopyrimidine Nucleosides
Chang, George,Mertes, Mathias P.
, p. 3625 - 3631 (2007/10/02)
The development of a direct and efficient palladium(0)-catalyzed biaryl coupling reaction permitted the synthesis of a series of N1-substituted 5-aryl-2,4-dioxopyrimidines.The physical and spectral properties of these compounds were determined and correlated by various linear free energy relationships.The relationships between the physical and spectral data with Hammett ? constants proved useful in analyzing the electron distribution of the heterocycle.Although a significant degree of orbital overlap and interaction between the substituents and the pyrimidine ring was observed, it is doubtful that the interactions are comparable to those of a benzene ring system.
