108672-20-4Relevant academic research and scientific papers
An investigation into the synthesis of some molecules related to methyl acarviosin
McDonough, Matthew J.,Stick, Robert V.,Tilbrook, D. Matthew G.,Watts, Andrew G.
, p. 233 - 241 (2007/10/03)
Methyl acarviosin is an impressive inhibitor of some glycoside hydrolases that process substrates containing α-D-glucosidic linkages. In an attempt to provide putative inhibitors for enzymes that process β-D-glucosidic linkages, we report an improved synthesis of a hydroxylated 'methyl β-acarviosin' and our efforts towards various deoxygenated versions of methyl β-acarviosin. As well, the synthesis of a 1,3-linked variant of methyl β-acarviosin is reported, together with an unsuccessful 'tether' approach to construct the crucial nitrogen linkage in the acarviosins.
SYNTHETIC RECEPTOR ANALOGUES: PREPARATION OF THE 3-O-METHYL, 3-C-METHYL, AND 3-DEOXY DERIVATIVES OF METHYL 4-O-α-D-GALACTOPYRANOSYL-β-D-GALACTOPYRANOSIDE (METHYL β-D-GALABIOSIDE)
Kihlberg, Jan,Frejd, Torbjoern,Jansson, Karl,Magnusson, Goeran
, p. 113 - 130 (2007/10/02)
Methyl β-D-galactopyranoside was transformed into methyl 2-O-benzyl- (5, 24percent) and 2-O-benzyloxymethyl-4,6-O-benzylidene-β-D-galactopyranoside (8, 60percent) in two and four steps respectively.Compounds 5 and 8 were then transformed into the correspo
