108686-16-4Relevant academic research and scientific papers
STEREOSELECTIVE HOMOALLYLIC ALCOHOL SYNTHESIS via SULPHONE α-CARBANION-MEDIATED COUPLING REACTIONS
Craig, Donald,Smith, Alison M.
, p. 2631 - 2632 (2007/10/02)
A novel method is described for the synthesis of homoallylic alcohols based on one-pot coupling reactions of sulphone stabilized carbanions with epoxides and aldehydes.
One-Pot Synthesis of Substituted Homoallylic Alcohols (3-Alkenols) and 1-Deuterio-3-alkenols; II. Extension to Ketone Enolates
Barluenga, Jose,Alvarez, Flora,Concellon, Jose M.,Bernad, Pablo,Yus, Miguel
, p. 318 - 320 (2007/10/02)
The reaction of different lithium ketone enolates with α-chloro carbonyl compounds followed by in situ reduction with lithium aluminium hydride or deuteride and final lithiation with lithium powder leads to the corresponding homoallylic or 1-deuterio homoallylic alcohols in a regioselective manner.
