108694-41-3

Basic information

• Product Name: Methanone, [5-chloro-2-(phenylamino)phenyl]phenyl-
• CAS NO: 108694-41-3
• Molecular Formula: C19H14ClNO
• Molecular Weight: 307.779
• Mol File: 108694-41-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Methanone, [5-chloro-2-(phenylamino)phenyl]phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [5-chloro-2-(phenylamino)phenyl]phenyl-(108694-41-3)
• EPA Substance Registry System: Methanone, [5-chloro-2-(phenylamino)phenyl]phenyl-(108694-41-3)

Safety Data

• Hazardous Substances Data: 108694-41-3(Hazardous Substances Data)

Upstream product

• 719-64-2 5-chloro-3-phenylanthranil 
• 3220-49-3 phenyl copper 
• 71-43-2 benzene 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 98-80-6 phenylboronic acid 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 591-50-4 iodobenzene 
• 591-51-5 phenyllithium 

Downstream Products

• 1246849-55-7 (E)-(5-chloro-2-(phenylamino)phenyl)(phenyl)methanone oxime 
• 95888-31-6 2-chloro-10-phenylacridine 
• 6321-64-8 2-chloro-10-phenylacridin-9(10H)-one 
• 108694-45-7 2'-benzoyl-4'-chloro-N-phenyl-2-azidoacetanilide 
• 108694-43-5 6-chloro-1,4-diphenyl-3,4-epoxy-2-quinolone 
• 108694-44-6 2'-benzoyl-4'-chloro-N-phenyl-2-iodoacetanilide 
• 108694-46-8 7-chloro-1,3-dihydro-1,5-diphenyl-2H-1,4-benzodiazepin-2-one 
• 108694-42-4 2'-benzoyl-4'-chloro-N-phenyl-2-chloroacetanilide 

Relevant articles and documents

Copper-Catalyzed Electrophilic Amination of Arylboronic Acids with Anthranils: An Access to N-Aryl-2-aminophenones

An efficient copper-catalyzed electrophilic amination strategy has been established for the rapid synthesis of N-aryl-2-aminophenones from readily available arylboronic acids/esters and anthranils. This protocol features good functional group tolerance, broad substrate scope, and operational simplicity. Moreover, a tandem C-H borylation and C-N coupling protocol has also been developed to transform simple arenes to the valuable N-aryl-2-aminophenones in one pot. Additionally, the synthetic potential of this methodology is further demonstrated by the synthesis of various useful N-heterocycles and derivatives.

Cobalt-Catalyzed Electrophilic Aminations with Anthranils: An Expedient Route to Condensed Quinolines

The reaction of various organozinc pivalates with anthranils provides anilines derivatives, which cyclize under acidic conditions providing condensed quinolines. Using alkenylzinc pivalates, electron-rich arylzinc pivalates or heterocyclic zinc pivalates produces directly the condensed quinolines of which several structures belong to new heterocyclic scaffolds. These N-heterocycles are of particular interest for organic light emitting diodes with their high photoluminescence quantum yields and long exciton lifetimes as well as for hole-transporting materials in methylammonium lead iodide perovskites solar cells due to an optimal band alignment for holes and a large bandgap.

Nickel-Catalyzed Transformations of 2,1-Benzisoxazoles with Organozinc Reagents

A novel transformation of 2,1-benzisoxazoles (anthranils) involving nitrogen-oxygen bond rupture with concomitant nitrogen-carbon bond formation by reaction with aryl-, methyl, or 2-thienylzinc chlorides in the presence of nickel catalyst is described.The products of the reaction are o-(substituted-amino)benzaldehydes and benzophenones, precursors of a series of heterocyclic derivatives, including acridines, quinolones, and the novel 7-chloro-1,3-dihydro-1,5-diphenyl-2H-1,4-benzodiazepin-2-one (21)