1087058-32-9

Basic information

• Product Name: (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-(4-methoxyphenyl)penta-2,4-dienamide
• Synonyms: (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-(4-methoxyphenyl)penta-2,4-dienamide
• CAS NO: 1087058-32-9
• Molecular Weight: 323.348
• Mol File: 1087058-32-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-(4-methoxyphenyl)penta-2,4-dienamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-(4-methoxyphenyl)penta-2,4-dienamide(1087058-32-9)
• EPA Substance Registry System: (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-(4-methoxyphenyl)penta-2,4-dienamide(1087058-32-9)

Safety Data

• Hazardous Substances Data: 1087058-32-9(Hazardous Substances Data)

Upstream product

• 94-62-2 Piperine 
• 136-72-1 piperic acid 
• 104-94-9 4-methoxy-aniline 
• 4711-72-2 piperic acid chloride 

Relevant articles and documents

Synthesis, antimicrobial, antioxidant and nematicidal activity of (2E,4E)-5-(Benzo[d] [1,3]dioxol-5yl)penta-2,4-dienamides

The amides of piperic acid have been synthesized via the condensation of piperic acid with amines. The structural characterization was done by IR, 1H-NMR, EI-MS and elemental analysis. The amides 3a-3o were evaluated for their biological activity. It has been found that among others the newly synthesized compound 3f, 3k, 3m, and 3o have great potential against root-knot nematode Meloidogyne incognita that usually affect tomato crop. These compounds exhibited 92, 96, 82 and 95% mortality rate at lethal concentration (LC50) 4.4, 3.4, 4.5 and 3.5 mg/mL, respectively. Conventionally used nematicide furadan was taken as standard. Compound 3h, 3c and, 3j exhibited significant anti-oxidant activities against 1,1-diphenylpicrylhydrazil (DPPH) radical with 80, 70 and 72% inhibition (EC50 = 625, 937 and 937.5 μg/mL), respectively. Ascorbic acid was used as standard. When tested for antimicrobial activity 3m was found to be the most active one showing zone of inhibition in the range of 18-30 mm against all tested microbial strains. Good biological activities of synthetic amides indicate their ability to behave as a good antimicrobial and nematicidal agent.