108761-33-7

Basic information

• Product Name: 6-CHLOROINDOXYL-1,3-DIACETATE
• Synonyms: 1-acetyl-6-chloro-1H-indol-3-yl acetate;(1-acetyl-6-chloroindol-3-yl) acetate;6-Chloro indoxyl-1,3-diacetate≥ 98% (HPLC);6-CHLOROINDOXYL-1,3-DIACETATE;ACETIC ACID 1-ACETYL-6-CHLORO-1H-INDOL-3-YL ESTER;6-CHLOROINDOLYL-1,3-DIACETATE;6-Chloro-3-indolyl 1,3-diacetate
• CAS NO: 108761-33-7
• Molecular Formula: C₁₂H₁₀ClNO₃
• Molecular Weight: 251.67
• Product Categories: substrate
• Mol File: 108761-33-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 111-113 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 376.951 °C at 760 mmHg
• Flash Point: 181.774 °C
• Appearance: /
• Density: 1.337 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: Store at -20
• CAS DataBase Reference: 6-CHLOROINDOXYL-1,3-DIACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLOROINDOXYL-1,3-DIACETATE(108761-33-7)
• EPA Substance Registry System: 6-CHLOROINDOXYL-1,3-DIACETATE(108761-33-7)

Safety Data

• Hazardous Substances Data: 108761-33-7(Hazardous Substances Data)

Usage

Chemical Properties

Yellow to yellowish brown powder

InChI:InChI=1/C12H10ClNO3/c1-7(15)14-6-12(17-8(2)16)10-4-3-9(13)5-11(10)14/h3-6H,1-2H3

Upstream product

• 108-24-7 acetic anhydride 
• 79-11-8 chloroacetic acid 
• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 50-84-0 2,4 dichlorobenzoic acid 
• 99282-79-8 2-carboxymethylamino-4-chlorobenzoic acid 
• 914221-22-0 2-(acetyl-carboxymethyl-amino)-4-chloro-benzoic acid 
• 936-08-3 2-bromo-4-chlorobenzoic acid 

Downstream Products

• 1629135-25-6 (S)-5-acetyl-7-chloro-4-phenyl-3,4-dihydropyrano[3,2-b]indol-2(5H)-one 
• 1629135-37-0 (R)-5-acetyl-7-chloro-4-phenyl-3,4-dihydropyrano[3,2-b]indol-2(5H)-one 
• 700838-52-4 [2-(1-(2'-bromobenzenesulfonyl)-6-chloro-1H-indol-3-yloxy)ethyl]dimethylamine 
• 133950-72-8 Nonanoic acid 6-chloro-1H-indol-3-yl ester 
• 114305-99-6 6-chloro-1H-indol-3-yl acetate 
• 149231-54-9 1-acetyl-6-chloro-indol-3-ol 
• 68095-16-9 1-acetyl-6-chloro-1,2-dihydro-3H-indol-3-one 

Relevant articles and documents

A simple procedure for the preparation of 6-chloro-3-acetoxy-1-acetylindole

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N1-Arylsulfonyl-3-piperazinyl indole derivatives were designed and identified as a novel class of 5-HT6 receptors ligands. All the compounds have high affinity and antagonist activity towards 5-HT6 receptor. The compound 7a (Ki = 3.4 nM, functional assay IC 50 = 310 nM) shows enhanced cognitive effect when tested in NORT and Morris water maze models. Synthesis, SAR and PK profile of these novel compounds constitute the subject matter of this Letter.

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