108774-33-0

Basic information

• Product Name: (1S,6S)-3,4-Dimethyl-6-phenyl-cyclohex-3-enecarboxylic acid methyl ester
• CAS NO: 108774-33-0
• Molecular Weight: 244.334
• Mol File: 108774-33-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,6S)-3,4-Dimethyl-6-phenyl-cyclohex-3-enecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,6S)-3,4-Dimethyl-6-phenyl-cyclohex-3-enecarboxylic acid methyl ester(108774-33-0)
• EPA Substance Registry System: (1S,6S)-3,4-Dimethyl-6-phenyl-cyclohex-3-enecarboxylic acid methyl ester(108774-33-0)

Safety Data

• Hazardous Substances Data: 108774-33-0(Hazardous Substances Data)

Upstream product

• 103-26-4 Methyl cinnamate 
• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 868070-20-6 triisopropyl((1-methoxy-2-methylprop-1-en-1-yl)oxy)silane 

Relevant articles and documents

Scalable and Highly Diastereo- and Enantioselective Catalytic Diels-Alder Reaction of α,β-Unsaturated Methyl Esters

Despite tremendous advances in enantioselective catalysis of the Diels-Alder reaction, the use of simple α,β-unsaturated esters, one of the most abundant and useful class of dienophiles, is still severely limited in scope due to their low reactivity. We report here a catalytic asymmetric Diels-Alder methodology for a large variety of α,β-unsaturated methyl esters and different dienes based on extremely reactive silylium imidodiphosphorimidate (IDPi) Lewis acids. Mechanistic insights from accurate domain-based local pair natural orbital coupled-cluster (DLPNO-CCSD(T)) calculations rationalize the catalyst control and stereochemical outcome.