108787-38-8Relevant academic research and scientific papers
Use of NPE-protecting groups for the preparation of oligonucleotides without using nucleophiles during the final deprotection
Avino,Eritja
, p. 2059 - 2069 (1994)
The preparation of O-(4-nitrophenyl)ethyl phosphoramidites and H- phosphonate derivatives of Npe protected nucleosides is described together with the use of these products to prepare oligodeoxynucleotides without using nucleophiles during the final deprot
New 2-(4-nitrophenyl)ethyl(Npe)- and 2-(4- nitrophenyl)ethoxycarbonyl(Npeoc)protected 2'-deoxyribonucleosides and their 3'-phosphoramidites - Versatile building blocks for oligonucleotide synthesis
Lang, Holger,Gottlieb, Margarete,Schwarz, Michael,Farkas, Silke,Schulz, Bernd S.,Himmelsbach, Frank,Charubala, Ramamurthy,Pfleiderer, Wolfgang
, p. 2172 - 2185 (2007/10/03)
A series of new base-protected and 5'-O-(4-monomethoxytrityl)- or 5'-O- (4,4'-dimethoxytrityl)-substituted 3'-(2-cyanoethyl diisopropylphosphoramidites) and 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidites] 52-66 and 67-82, respectively, are prepare
A study on the use of phenylacetyl disulfide in the solid-phase synthesis of oligodeoxynucleoside phosphorothioates
Roelen, H. C. P. F.,Kamer, P. C. J.,Elst, H. van den,Marel, G. A. van der,Boom, J. H. van
, p. 325 - 331 (2007/10/02)
Sulfurization of protected internucleosidic phosphite triesters can be conveniently executed with the easily accessible reagent, phenylacetyl disulfide (1).High-quality oligodeoxynucleotides containi
New Approach to the Synthesis of Deoxyribonucleoside Phosphoramidite Derivatives
Hamamoto, Shoji,Takaku, Hiroshi
, p. 1401 - 1404 (2007/10/02)
The deoxyribonucleoside phosphoramidites with various protecting groups at phosphorus have been prepared rapidly in good yields in one-pot reaction from bis(diisopropylamino)chlorophosphine as a new phosphitylating agent without isolation of bis(diisopropylamino)alkoxyphosphines.
