153120-90-2

Upstream product

• 100-27-6 2-(4-nitrophenyl)ethanol 

Downstream Products

• 156159-78-3 5'-O-(2-dansylethoxycarbonyl)-thymidine 3'-<2-(4-nitrophenyl)ethyl N,N-diisopropylphosphoramidite> 
• 156159-79-4 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-<2-(4-nitrophenyl)ethoxycarbonyl>cytidine 3'-<2-(4-nitrophenyl)ethyl N,N-diisopropylphosphoramidite> 
• 156159-80-7 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl N,N-diisopropylphosphoramidite> 
• 156159-81-8 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N²-<2-(4-nitrophenyl)ethoxycarbonyl>-O⁶-<2-(4-nitrophenyl)ethyl>guanosine 3'-<2-(4-nitrophenyl)ethyl N,N-diisopropylphosphoramidite> 
• 177084-36-5 Hexadecanoic acid 2-{[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-[2-(4-nitro-phenyl)-ethoxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester 
• 177084-37-6 Tetradecanoic acid 2-{[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-[2-(4-nitro-phenyl)-ethoxy]-phosphoryloxy}-1-tetradecanoyloxymethyl-ethyl ester 
• 177084-38-7 Phosphoric acid (2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 2,3-bis-hexadecyloxy-propyl ester 2-(4-nitro-phenyl)-ethyl ester 
• 177084-40-1 3'-deoxy-N⁶,2'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 5'-<(2RS)-2,3-bis(hexadecanoyloxy)-propyl 2-(4-nitrophenyl)ethyl phosphate> 
• 177084-44-5 3'-deoxy-N⁶,5'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 2'-<(2RS)-2,3-bis(hexadecanoyloxy)-propyl 2-(4-nitrophenyl)ethyl phosphate> 
• 177084-41-2 3'-deoxy-N⁶,2'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 5'-<(2RS)-2,3-bis(tetradecanoyloxy)-propyl 2-(4-nitrophenyl)ethyl phosphate> 
• 177084-45-6 3'-deoxy-N⁶,5'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 2'-<(2RS)-2,3-bis(tetradecanoyloxy)-propyl 2-(4-nitrophenyl)ethyl phosphate> 
• 177084-42-3 3'-deoxy-N⁶,2'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 5'-<(2RS)-2,3-bis(hexadecycloxy)propyl 2-(4-nitrophenyl)ethyl phosphate> 
• 177084-46-7 3'-deoxy-N⁶,5'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 2'-<(2RS)-2,3-bis(hexadecyloxy)propyl 2-(4-nitrophenyl)ethyl phosphate> 

Relevant academic research and scientific papers

2',5'-phosphorothioate/phosphodiester oligoadenylates and anti-viral uses thereof

Optically active antiviral compounds having the formula STR1 wherein m is 0, 1, 2, or 3; n and q are selected from the group of 0 and 1, provided that n and q may not both be zero; and R, R1, and R2 are independently of each other selected from the group consisting of oxygen and sulfur, provided that all R, R1 and R2, may not be oxygen, and further provided that all R, R1, and R2 may not be sulfur. The compounds possess increased antiviral activity and/or metabolic stability.

The 2-Dansylethoxycarbonyl (=2-{[5-dimethylamino)naphthalen-1-yl]sulfonyl}ethoxycarbonyl; Dnseoc) group for protection of the 5'-hydroxy function in oligodeoxyribonucleotide synthesis

Use of the 2-dansylethoxycarbonyl (=2-{[5-(dimethylamino)naphthalen-1-yl]sulfonyl])ethoxycarbonyl; Dnseoc) group as an intermediate 5'-OH protecting group in oligodeoxyribonucleotide synthesis using the automated phosphoramidite approach is described in a model study to an alternative strategy in RNA synthesis.