108788-48-3

Upstream product

• 23558-05-6 3-O-benzyl-1,2-O-isopropylidene-1,5-D-xylo-dialdofuranose 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 105-36-2 ethyl bromoacetate 
• 34370-89-3 (3aR,5R,6R,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 

Downstream Products

• 139534-92-2 (3aS,5R,6S,6aR)-6-Benzyloxy-5-dimethoxymethyl-tetrahydro-furo[3,2-b]furan-2-one 
• 108182-71-4 (Z)-3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-α-D-xylo-hept-5-eno-1,4-furanose 
• 500908-09-8 ethyl [5-amino-3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene]-heptofuranuronate 
• 1071912-14-5 ethyl 1,2-O-isopropylidene-3-O-benzyl-5-nitromethyl-5,8-dideoxy-β-L-ido-heptofuranuronate 
• 145741-65-7 (-)-(2E)-(4R,5R,6R)-5-Benzyloxy-4,6-dihydroxy-7-(1',3'-dithiolan-2'-yl)hept-2-enoate 
• 145741-53-3 (+)-(1S,2S,3R,4S)-2-Benzyloxy-4-(2'-hydroxyethyl)cyclopentane-1,3-diol 
• 145741-67-9 (+)-(1S,2S,3R,4R)-Ethyl 5-benzyloxy-3-tert-butyldimethylsilyloxy-4-ethoxycarbonylmethylcyclopentan-1-ol 
• 145741-52-2 (+)-(1S,2S,3R,4S)-2-Benzyloxy-1,3-bis(tert-butyldimethylsilyloxy)-4-ethoxycarbonylmethylcyclopentane 
• 145741-66-8 (-)-(2E)-(4R,5S,6R)-5-Benzyloxy-4-tert-butyldimethylsilyloxy-7-(1',3'-dithiolan-2'-yl)-6-hydroxyhept-2-enoate 
• 108788-55-2 6-azide-3-O-benzyl-6-deoxy-1,2-O-isopropylidene-7-O-p-toluenesulfonyl-α-D-glycero-L-ido-heptofuranose 
• 108788-54-1 6-azide-3-O-benzyl-6-deoxy-1,2-O-isopropylidene-7-O-p-toluenesulfonyl-α-L-glycero-D-gluco-heptofuranose 
• 108788-51-8 6-azide-3-O-benzyl-6-deoxy-1,2-O-isopropylidene-α-D-glycero-L-ido-heptofuranose 
• 108788-50-7 6-azide-3-O-benzyl-6-deoxy-1,2-O-isopropylidene-α-L-glycero-D-gluco-heptofuranose 
• 108788-59-6 5,7-anhydro-6-azide-3-O-benzyl-6-deoxy-1,2-O-isopropylidene-α-D-glycero-L-ido-heptofuranose 

Relevant academic research and scientific papers

Ethoxycarbonylmethylenetriphenylphosphorane in carbohydrate chemistry : An easy access to functionalised 2-deoxy-3,6-anhydrohexono-1,4-lactones

2-Deoxy-3,6-anhydrohexono-1,4-lactones are obtained efficiently from aldehydosugars in a two-step sequence involving a Wittig followed by acid-catalysed methanolysis.

Wittig-type olefination catalyzed by PEG-telluride

Soluble poly(ethylene glycol) (PEG)-supported telluride 2 was designed and synthesized for catalytic Wittig-type reactions. It was found that the catalytic loading could be reduced from 20 to 2 mol % by the introduction of PEG (even to 0.5 mol % when some telluride salts were used as the catalyst). Under the catalytic reaction conditions, a wide variety of aldehydes with different structures could react with bromoacetate to afford β-substituted or α,β-disubstituted unsaturated esters in high yields with excellent E-stereoselectivity. The modified process, by using sodium bisulfite instead of triphenyl phosphite, represented a very simple product isolation procedure. The roles of PEG for promoting the ylide formation and stabilizing the catalytic species were disclosed. The mechanism was also studied.

Synthesis of glycosylated β-amino acids as new class of antitubercular agents

A series of glycosylated β-amino acids was prepared and evaluated against Mycobacterium tuberculosis, M. avium, M. fortuitum and M. smegmatis. The compounds were designed to mimic the enzyme D-alanine racemase and glycosyl transferase involved in the bios

Intramolecular Michael addition of benzylamine to sugar derived α,β-unsaturated ester: A new diastereoselective synthesis of a higher homologue of 1-deoxy-L-ido-nojirimycin

The diastereoselective intramolecular Michael addition of the benzylamine generated in situ from hemiacetal 3 leads to the lactone 4a with the required homoazasugar ring skeleton; reduction of the lactone functionality and removal of the protecting groups

Total Synthesis of Griseolic Acid Derivatives from D-Glucose

Griseolic acid, 1, is a potent nonselective cyclic nucleotide-phosphodiesterase inhibitor isolated from Streptomyces griseoaurantiacus.Recently, preparation of several griseolic acid derivatives, including 3, has been reported.We have completed the chiral