108825-21-4

Basic information

• Product Name: 6-(benzyloxy)quinoline
• Synonyms: 6-(benzyloxy)quinoline
• CAS NO: 108825-21-4
• Molecular Weight: 235.285
• Mol File: 108825-21-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-(benzyloxy)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(benzyloxy)quinoline(108825-21-4)
• EPA Substance Registry System: 6-(benzyloxy)quinoline(108825-21-4)

Safety Data

• Hazardous Substances Data: 108825-21-4(Hazardous Substances Data)

Upstream product

• 580-16-5 6-hydroxyquinoline 
• 100-44-7 benzyl chloride 

Downstream Products

• 580-16-5 6-hydroxyquinoline 
• 1337882-50-4 6-(benzyloxy)-3-bromoquinoline 
• 476661-72-0 6-(benzyloxy)quinoline 1-oxide 
• 1497411-60-5 C₂₁H₂₃NO₄ 
• 1497411-44-5 C₂₆H₂₅NO₃ 
• 1352302-93-2 2,3,4,2',3',4',6'-hepta-O-benzyl-6-O-(2-(6-benzyloxyquinolinium-1-yl)acetyl)-α,α-D-trehalose bromide 
• 1352302-97-6 2,3,4,2',3',4',6'-hepta-O-benzyl-6-(6-benzyloxyquinolinium-1-yl)-6-deoxy-α,α-D-trehalose trifluoromethanesulfonate 
• 1275591-27-9 6-(benzyloxy)-8-phenylquinoline 
• 75893-80-0 6-benzilossi-1,2,3,4-tetraidrochinolina 

Relevant articles and documents

PS-IIDQ: a supported coupling reagent for efficient and general amide bond formation

Polystyrene-IIDQ, a polymer-supported coupling reagent, was synthesized in three steps from Merrifield resin in 86% overall conversion. This reagent efficiently coupled carboxylic acids to amines in good yields and high purities, required no pre-activation step, and was tolerant of the order of reagent addition. PS-IIDQ was observed to be more efficient than polymer-supported carbodiimides (PS-EDC and PS-DCC) and gave higher yields than HATU for general amide bond formation, including the coupling of anilines and hindered substrates. When evaluated with five carboxylic acids and nine amines (including anilines and secondary amines) PS-IIDQ gave an average isolated yield of 73%.